10186-63-7

Basic information

• Product Name: METHYL 2-METHOXYTETRAFLUOROPROPIONATE
• Synonyms: Propionicacid, 2,3,3,3-tetrafluoro-2-methoxy-, methyl ester (7CI,8CI); Methyl2,3,3,3-tetrafluoro-2-methoxypropanoate
• CAS NO: 10186-63-7
• Molecular Formula: C₅H₆F₄O₃
• Molecular Weight: 190.1
• Mol File: 10186-63-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 119-122°C
• Flash Point: 50.8°C
• Appearance: /
• Density: 1.331g/cm³
• Vapor Pressure: 2.24mmHg at 25°C
• Refractive Index: 1.332
• CAS DataBase Reference: METHYL 2-METHOXYTETRAFLUOROPROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-METHOXYTETRAFLUOROPROPIONATE(10186-63-7)
• EPA Substance Registry System: METHYL 2-METHOXYTETRAFLUOROPROPIONATE(10186-63-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• HazardClass: IRRITANT
• Hazardous Substances Data: 10186-63-7(Hazardous Substances Data)

Usage

General Description

Methyl 2-methoxytetrafluoropropionate is a synthetic chemical compound commonly used as a fluoro-surfactant in various industries, particularly in the production of polymers, adhesives, and coatings. It is known for its low surface tension and excellent wetting properties, making it an effective additive for improving the spreadability and durability of products. This chemical is also used in the formulation of water and oil repellent coatings for textiles, paper, and leather. Despite its widespread industrial application, methyl 2-methoxytetrafluoropropionate is known to be potentially hazardous to human health and the environment and should be handled with caution.

InChI:InChI=1/C5H6F4O3/c1-11-3(10)4(6,12-2)5(7,8)9/h1-2H3

Upstream product

• 67-56-1 methanol 
• 85036-47-1 α-methoxytetrafluoropropionyl fluoride 
• 71917-15-2 2,3-epoxyperfluoropentane 
• 124-41-4 sodium methylate 
• 129880-36-0 Caesium; 2,3,3,3-tetrafluoro-2-methoxy-propionate 
• 129880-35-9 Potassium; 2,3,3,3-tetrafluoro-2-methoxy-propionate 
• 123202-05-1 Sodium; 2,3,3,3-tetrafluoro-2-methoxy-propionate 
• 532-32-1 sodium benzoate 
• 378-77-8 sodium pentafluoropropionate 
• 428-59-1 Hexafluoropropene oxide 
• 366-18-7 [2,2]bipyridinyl 
• 66-71-7 1,10-Phenanthroline 
• 67-68-5 dimethyl sulfoxide 

Downstream Products

• 421-20-5 Methyl fluorosulfonate 
• 431-47-0 trifluoroacetic acid-methyl ester 
• 13089-11-7 methyl 3,3,3-trifluoropyruvate 
• 19390-75-1 methyl 3,3,3-trifluoro-2,2-dihydroxypropanoate 
• 19607-21-7 methyl 3,3,3-trifluoro-2-hydroxy-2-methoxypropanoate 
• 593-53-3 Methyl fluoride 
• 121-69-7 N,N-dimethyl-aniline 
• 100-61-8 N-methylaniline 
• 124315-28-2 α,α-Bis(3,5-dimethyl-4-hydroxyphenyl)trifluoropropionic acid methyl ester 
• 10186-65-9 2.3.3.3-Tetrafluor-2-methoxy-propionsaeureamid 

Relevant articles and documents

Hexafluoropropylene oxide-alcohol: A convenient system for silica dissolution

A new method of silica dissolution is described. It involves the formation of a stable SiF4 n ROH complex (1, 1a) just from SiO2 and anhydrous alcoholic HF generated in situ from commercially available hexafluoropropene oxide. Alcoholic SiF4 complexes can be easily converted to different organosilicon compounds of the type SiF4L 2 and (LH)2SiF6 [L = 1,10-phenantroline (2a), 2,2'-dipyridyl (2b), Me2SO (2c), pyridine (2d), triethanolamine (3a)]. Different silica-containing compounds can be used in this strategysilicagel, sand, alumosilicates, and even rice husk. Copyright Taylor & Francis Group, LLC.

Preparation method of 2-fluoro-2-alkyloxy trifluoropropionate

The invention discloses a preparation method of 2-fluoro-2-alkyloxy trifluoropropionate. In the presence of an organic alkali and/or an inorganic alkali, hexafluoropropylene oxide and alkyl alcohols carry out reactions to obtain corresponding 2-fluoro-2-alkyloxy trifluoropropionate. The provided method has the advantages of suitable reaction temperature, high reaction yield, good selectivity, little amount of waste solid, waste water, and waste gas, and easiness for industrialization. The prepared 2-fluoro-2-alkyloxy trifluoropropionate can be used as a trifluoromethylation reagent for the synthesis of novel medicines and pesticides.

Methyl 3,3,3-trifluoropyruvate: An improved procedure starting from hexafluoropropene-1,2-oxide; identification of byproducts

Optimized laboratory-scale preparation of methyl 3,3,3-trifluoropyruvate (3, MTFP) has been developed starting from industrial hexafluoropropene-1,2-oxide (1, HFPO) via methyl 2,3,3,3-tetrafluoro-2-methoxypropanoate (2, MTPr), which was transformed to 3 using sulfuric acid with isolated yields up to 81%. Byproducts formed in the transformation of 2 to 3, viz. methyl trifluoroacetate (4, MTAc), methyl 3,3,3-trifluoropyruvate hydrate (5), methyl hemiacetal of trifluoropyruvate (6), a dimer of methyl 3,3,3-trifluoropyruvate hydrate (7, DimMTP), and methyl fluorosulfate (8, Sulf) were identified and their amounts determined under various experimental conditions. Potential reaction pathways leading to the formation of the byproducts are discussed.