101863-15-4

Basic information

• Product Name: 4-methyl-N-(piperidin-1-yl)benzenesulfonamide
• Synonyms: 4-methyl-N-(piperidin-1-yl)benzenesulfonamide
• CAS NO: 101863-15-4
• Molecular Weight: 254.353
• Mol File: 101863-15-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-methyl-N-(piperidin-1-yl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-(piperidin-1-yl)benzenesulfonamide(101863-15-4)
• EPA Substance Registry System: 4-methyl-N-(piperidin-1-yl)benzenesulfonamide(101863-15-4)

Safety Data

• Hazardous Substances Data: 101863-15-4(Hazardous Substances Data)

Upstream product

• 2213-43-6 1-Aminopiperidine 
• 98-59-9 p-toluenesulfonyl chloride 
• 624-31-7 4-tolyl iodide 

Downstream Products

• 56410-24-3 N,N'-bis(p-toluenesulfonyl)hydroxylamine 

Relevant articles and documents

Palladium-catalyzed aminosulfonylation of aryl halides

The palladium-catalyzed three-component coupling of aryl iodides, sulfur dioxide, and hydrazines to deliver aryl N-aminosulfonamides is described. The colorless crystalline solid DABCO· (SO2)2 was used as a convenient source of sulfur dioxide. The reaction tolerates significant variation of both the aryl iodide and hydrazine coupling partners.

A palladium-catalyzed reaction of aryl halides, potassium metabisulfite, and hydrazines

Aryl N-aminosulfonamides could be easily produced via a palladium-catalyzed coupling of aryl halides, potassium metabisulfite, and hydrazines. Potassium metabisulfite is an excellent equivalent of sulfur dioxide in the reaction of palladium-catalyzed aminosulfonylation. The Royal Society of Chemistry 2012.