1023813-80-0

Basic information

• Product Name: 5,6,7,8-Tetrahydro-[1,8]naphthyridine-3-bromide
• Synonyms: 5,6,7,8-Tetrahydro-[1,8]naphthyridine-3-bromide;6-BROMO-1,2,3,4-TETRAHYDRO-1,8-NAPHTHYRIDINE;1,8-Naphthyridine, 6-bromo-1,2,3,4-tetrahydro-
• CAS NO: 1023813-80-0
• Molecular Formula: C8H9BrN2
• Molecular Weight: 213.07446
• Mol File: 1023813-80-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 327.7±42.0 °C(Predicted)
• Appearance: /
• Density: 1.68±0.1 g/cm3(Predicted)
• PKA: 9.37±0.20(Predicted)
• CAS DataBase Reference: 5,6,7,8-Tetrahydro-[1,8]naphthyridine-3-bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,7,8-Tetrahydro-[1,8]naphthyridine-3-bromide(1023813-80-0)
• EPA Substance Registry System: 5,6,7,8-Tetrahydro-[1,8]naphthyridine-3-bromide(1023813-80-0)

Safety Data

• Hazardous Substances Data: 1023813-80-0(Hazardous Substances Data)

Usage

General Description

5,6,7,8-Tetrahydro-[1,8]naphthyridine-3-bromide is a chemical compound that belongs to the family of naphthyridine derivatives. It is a brominated compound with a molecular formula of C10H13BrN2. This chemical compound has potential applications in the field of medicinal chemistry due to its structural properties and pharmacological activities. It can be used as a building block for the synthesis of biologically active molecules and pharmaceutical drugs. Additionally, its bromine substituent can provide specific reactivity and physiological effects in biological systems. Further research and studies on this compound may reveal its potential as a valuable tool in pharmaceutical development and other scientific applications.

Upstream product

• 335031-10-2 6-bromo-2-oxo-1,2,3,4-tetrahydro-1,8-naphthyridine-3-carboxylic acid methyl ester 
• 335033-38-0 2-amino-5-bromo-3-(bromomethyl)pyridine hydrobromide 
• 443956-55-6 (2-amino-5-bromopyridine-3-yl)methanol hydrobromide 
• 23612-57-9 (2-amino-3-pyridinyl)methanol 
• 5345-47-1 2-aminopyridin-3-carboxylic acid 
• 129686-16-4 6-bromo-3,4-dihydro-1,8-naphthyridine-2(1H)-one 

Downstream Products

• 335030-38-1 6-bromo-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester 
• 676515-34-7 6-bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one 
• 1613148-03-0 (R)-N,N-bis(tert-butoxycarbonyl)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)pyridin-2-amine 

Relevant articles and documents

CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS

The present disclosure relates to modulators, such as inhibitors, of at least one pathway chosen from USP28 and USP25, pharmaceutical compositions comprising the inhibitors, and methods of using the inhibitors. The modulators, such as inhibitors, of at least one pathway chosen from USP28 and USP25 can be useful in the treatment of cancers, among other ailments.

ALDOSTERONE SYNTHASE INHIBITORS

The present invention relates to compounds of the formulas (IA) and (IB) and pharmaceutically acceptable salts thereof, wherein A and R1 - R6, are as defined herein. The invention also relates to pharmaceutical compositions comprisin

ALDOSTERONE SYNTHASE INHIBITORS

The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2. R3, R4, R5, R6, R7, W, Y, m and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.