1028-19-9

Basic information

• Product Name: 1-(4'-methylbenzenesulfonyl)-1H-benzo[d][1.2.3]triazole
• Synonyms: 1-(4'-methylbenzenesulfonyl)-1H-benzo[d][1.2.3]triazole
• CAS NO: 1028-19-9
• Molecular Weight: 273.315
• Mol File: 1028-19-9.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 1-(4'-methylbenzenesulfonyl)-1H-benzo[d][1.2.3]triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4'-methylbenzenesulfonyl)-1H-benzo[d][1.2.3]triazole(1028-19-9)
• EPA Substance Registry System: 1-(4'-methylbenzenesulfonyl)-1H-benzo[d][1.2.3]triazole(1028-19-9)

Safety Data

• Hazardous Substances Data: 1028-19-9(Hazardous Substances Data)

Upstream product

• 6380-13-8 4-methyl-N-(2-nitrophenyl)benzene sulfonamide 
• 88-74-4 2-nitro-aniline 
• 98-59-9 p-toluenesulfonyl chloride 
• 3624-90-6 N-tosyl-1,2-diaminobenzene 
• 95-14-7 1,2,3-Benzotriazole 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 462-80-6 benzyne 
• 941-55-9 4-toluenesulfonyl azide 
• 21050-95-3 N-chlorobenzotriazole 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 536-57-2 p-toluene sulfinic acid 

Downstream Products

• 4703-22-4 N-tosylpiperidine 
• 7510-48-7 N-(3-bromophenyl)-4-methyl-benzenesulfonamide 
• 68-34-8 phenyl toluenesulfonamide 
• 95-14-7 1,2,3-Benzotriazole 
• 77597-96-7 α-(4-tolylsulfonyl)phenylacetonitrile 
• 941-55-9 4-toluenesulfonyl azide 
• 161768-42-9 N-[(E)-1-(1H-1,2,3-benzotriazol-1-yl)(phenyl)methylidene]aniline 
• 161768-52-1 (E)-N-(1-(1H-benzo[d][1,2,3]triazol-1-yl)ethylidene)aniline 
• 104368-08-3 α-<(4-methylphenyl)sulfonyl>benzeneacetic acid ethyl ester 
• 76283-77-7 1-benzenesulfonylmethanesulfonyl-4-methylbenzene 

Relevant articles and documents

One-pot synthesis of N-imidoylbenzotriazoles via benzotriazole-mediated Beckmann rearrangement of oximes

(Matrix presented) N-Imidoylbenzotriazoles 5a-I are obtained under mild conditions in variable yields (20-87%) by reactions of oximes 2a-I with BtTs 1 via a Beckmann rearrangement.

Synthesis of sulfonyl azides

1-(Alkylsulfonyl)- and 1-(arylsulfonyl)benzotriazoles react with sodium azide in acetonitrile to give the corresponding alkanesulfonyl and arenesulfonyl azides. Georg Thieme Verlag Stuttgart.

Nickel-Catalyzed Reductive Cross-Coupling of N-Acyl and N-Sulfonyl Benzotriazoles with Diverse Nitro Compounds: Rapid Access to Amides and Sulfonamides

Herein we report a Ni-catalyzed reductive transamidation of conveniently available N-acyl benzotriazoles with alkyl, alkenyl, and aryl nitro compounds, which afforded various amides with good yields and a broad substrate scope. The same catalytic reaction conditions were also applicable for N-sulfonyl benzotriazoles, which could undergo smooth reductive coupling with nitroarenes and nitroalkanes to afford the corresponding sulfonamides.

Synthesis of Structurally Diverse Benzotriazoles via Rapid Diazotization and Intramolecular Cyclization of 1,2-Aryldiamines

An operationally simple method has been developed for the preparation of N-unsubstituted benzotriazoles by diazotization and intramolecular cyclization of a wide range of 1,2-aryldiamines under mild conditions, using a polymer-supported nitrite reagent and p-tosic acid. The functional group tolerance of this approach was further demonstrated with effective activation and cyclization of N-alkyl, -aryl, and -acyl ortho-aminoanilines leading to the synthesis of N1-substituted benzotriazoles. The synthetic utility of this one-pot heterocyclization process was exemplified with the preparation of a number of biologically and medicinally important benzotriazole scaffolds, including an α-amino acid analogue.