103-43-5

Basic information

• Product Name: DIBENZYL SUCCINATE
• Synonyms: TIMTEC-BB SBB006245;SUCCINIC ACID DIBENZYL ESTER;SPASMINE;Butanedioic acid, bis(phenylmethyl) ester;BENZYL SUCCINATE;DIBENZYL SUCCINATE;butanedioic acid dibenzyl ester;DIBENZYL ETHANE-1,2-DICARBOXYLATE
• CAS NO: 103-43-5
• Molecular Formula: C₁₈H₁₈O₄
• Molecular Weight: 298.33
• EINECS: 203-110-9
• Product Categories: Pharmaceutical Intermediates
• Mol File: 103-43-5.mol
• Article Data: 11

Chemical Properties

• Melting Point: 42-43°C
• Boiling Point: 245°C/15mm
• Flash Point: 245°C/15mm
• Appearance: /
• Density: 1.256
• Vapor Pressure: 3.82E-07mmHg at 25°C
• Refractive Index: 1.5960
• Water Solubility: Insoluble in water.
• BRN: 1916056
• CAS DataBase Reference: DIBENZYL SUCCINATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIBENZYL SUCCINATE(103-43-5)
• EPA Substance Registry System: DIBENZYL SUCCINATE(103-43-5)

Safety Data

• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.
• Hazardous Substances Data: 103-43-5(Hazardous Substances Data)

Usage

Description

Dibenzyl succinate is an organic compound that serves as a versatile intermediate in the synthesis of various organic chemicals. It is a white crystalline powder with almost no taste and exhibits chemical properties such as solubility in alcohol, ether, chloroform, and both fixed and volatile oils, while being insoluble in water. Dibenzyl succinate is also combustible.

Uses

Used in Organic Chemical Synthesis:
Dibenzyl succinate is used as an organic chemical synthesis intermediate for the production of a wide range of compounds. Its unique structure allows it to be a valuable building block in the creation of various organic molecules, contributing to the development of new materials and chemicals.
Used in Medicine (Antispasmodic):
In the medical field, dibenzyl succinate is utilized as an antispasmodic agent. It helps to relieve muscle spasms and cramps, providing relief to patients suffering from various conditions that cause involuntary muscle contractions. Its effectiveness in this application is attributed to its ability to interact with the muscles and nerves, thereby reducing the frequency and intensity of spasms.

InChI:InChI=1/C18H18O4/c19-17(21-13-15-7-3-1-4-8-15)11-12-18(20)22-14-16-9-5-2-6-10-16/h1-10H,11-14H2

Upstream product

• 150-90-3 sodium succinate 
• 100-44-7 benzyl chloride 
• 88210-83-7 mercapto-succinic acid dibenzyl ester 
• 110-15-6 succinic acid 
• 111-20-6 1,10-decanedioic acid 
• 103-83-3 N,N'-dimethylbenzylamine 
• 106-65-0 Dimethyl succinate 
• 100-51-6 benzyl alcohol 
• 543-20-4 succinoyl dichloride 
• 108-30-5 succinic acid anhydride 
• 74-85-1 ethene 
• 201230-82-2 carbon monoxide 
• 140-11-4 Benzyl acetate 
• 620-05-3 iodomethylbenzene 

Downstream Products

• 1350373-52-2 3-((benzyloxy)carbonyl)-5-methylhex-3-enoic acid ethyl ester 
• 1350373-51-1 3-((benzyloxy)carbonyl)-5-methylhex-3-enoic acid 
• 6946-88-9 3-(propoxycarbonyl)propanoic acid 
• 925-15-5 dipropyl succinate 
• 103-40-2 succinic acid monobenzyl ester 

Relevant articles and documents

Palladium–Bis(carbene) Catalysts for the Bisalkoxycarbonylation of Olefins to Succinic Diesters

A series of Pd-bis(NHC) (NHC = N-heterocyclic carbene) complexes possessing various anions and substituents were used in the bisalkoxycarbonylation of olefins (α-olefins and ethylene) to afford industrially useful succinic diesters in modest to good yields. The influence of different ligands and counteranions of the Pd complexes on their catalytic activity was assessed, and it was found that dimeric Pd–bis(NHC)Br was the best catalyst for the bisalkoxycarbonylation reactions. The structure of dimeric Pd–bis(NHC)Br was confirmed by X-ray crystallographic analysis.

A Mild, General, Metal-Free Method for Desulfurization of Thiols and Disulfides Induced by Visible-Light

A visible-light-induced metal-free desulfurization method for thiols and disulfides has been explored. This radical desulfurization features mild conditions, robustness, and excellent functionality compatibility. It was successfully applied not only to the desulfurization of small molecules, but also to peptides.

Desulfurization method of organic compounds containing mercapto or disulfide bond

The invention relates to a desulfurization method of organic compounds, in particular, organic compounds containing mercapto or a disulfide bond. The method comprises following steps: dissolving organic compounds containing mercapto or a disulfide bond by a solvent; adding a phosphine reagent and an initiator; and carrying out reactions in the presence of light to convert the substrate into corresponding desulfurization products. The organic compounds containing mercapto or a disulfide bond is R-SH or R-S-S-R; wherein R represents a primary carbon group, a secondary carbon group, a tertiary carbon group, an aryl group, or an acyl group. The reactions do not need any metal, and the reaction conditions are mild. Moreover, the desulfurization method has the advantages of high yield, wide substrate application range, and multiple suitable solvents, and is widely suitable for multiple kinds of mercapto-removing reactions and desulfurization reactions of disulfide.