103675-56-5 Usage
Description
1-O-Trityl-sn-glycero-3-phosphocholine is a white solid that serves as an intermediate in the synthesis of glycerophospholipids. These glycerophospholipids act as regulators of various enzyme activities, making 1-O-Trityl-sn-glycero-3-phosphocholine a crucial compound in the field of biochemistry and pharmaceuticals.
Uses
1. Used in Pharmaceutical Industry:
1-O-Trityl-sn-glycero-3-phosphocholine is used as an intermediate for the synthesis of glycerophospholipids, which are essential for regulating various enzyme activities. This application is crucial in the development of drugs targeting enzyme-related diseases and conditions.
2. Used in Biochemical Research:
1-O-Trityl-sn-glycero-3-phosphocholine is used as a research tool in biochemistry to study the role of glycerophospholipids in cellular processes and their interactions with enzymes. This helps in understanding the underlying mechanisms of various biological functions and potential therapeutic targets.
3. Used in Drug Development:
1-O-Trityl-sn-glycero-3-phosphocholine is used as a starting material for the development of new drugs that target enzyme activities regulated by glycerophospholipids. This can lead to the creation of novel therapeutics for a wide range of diseases and conditions.
4. Used in Diagnostic Applications:
1-O-Trityl-sn-glycero-3-phosphocholine can be employed in the development of diagnostic tools and assays that measure enzyme activities regulated by glycerophospholipids. This can aid in the early detection and monitoring of enzyme-related diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 103675-56-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,6,7 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 103675-56:
(8*1)+(7*0)+(6*3)+(5*6)+(4*7)+(3*5)+(2*5)+(1*6)=115
115 % 10 = 5
So 103675-56-5 is a valid CAS Registry Number.
103675-56-5Relevant articles and documents
Synthetic phospholipids as specific substrates for plasma endothelial lipase
Papillon, Julien P.N.,Pan, Meihui,Brousseau, Margaret E.,Gilchrist, Mark A.,Lou, Changgang,Singh, Alok K.,Stawicki, Todd,Thompson, James E.
, p. 3514 - 3517 (2016)
We designed and prepared synthetic phospholipids that generate lyso-phosphatidylcholine products with a unique mass for convenient detection by LC–MS in complex biological matrices. We demonstrated that compound 4, formulated either as a Triton X-100 emulsion or incorporated in synthetic HDL particles can serve as a substrate for plasma EL with useful specificity.
Synthesis of phosphatidylcholines containing ricinoleic acid
Borsotti, Gianpietro,Guglielmetti, Gianfranco,Spera, Silvia,Battistel, Ezio
, p. 10219 - 10227 (2007/10/03)
1,2-Diricinoleoyl- and 1-ricinoleoyl-2-oleoyl-sn-glycero-3-phosphocholine were synthesised with good yields. The synthesis started with the preparation of ricinoleic acid from castor oil. The choice of a suitable agent to protect the -OH group of ricinoleic acid was a key factor to afford the final products. Several protecting groups were assayed but only β-methoxyethoxymethyl chloride (MEMCl) and 2,2,2-trichloroethyl chloroformate (TRECCl) gave reasonable yields and good optical purities of the final products. The overall yields for 1,2-diricinoleoyl-sn-glycero-3-phosphocholine and 1-ricinoleoyl-2-oleoyl-sn-glycero-3-phosphocholine were 32.1% (with respect to ricinoleic acid methyl ester using TREC as protecting group) and 10.3% (with respect to 1-trityl-glycero-3-phosphocholine), respectively.
