103634-10-2

Basic information

• Product Name: [R-(Z)]-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt
• Synonyms: [R-(Z)]-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt;(7R,17Z)-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt;[R-(Z)]-4-Hydroxy-N,N,N-trimethyl-9-oxo-7-[(triphenylmethoxy)methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium inner salt 4-oxide
• CAS NO: 103634-10-2
• Molecular Formula: C₄₅H₆₆NO₇P
• Molecular Weight: 764
• Product Categories: Fatty Acid Derivatives & Lipids;Glycerols;Phosphorylcholine Derivatives;Glycerols, Fatty Acid Derivatives & Lipids, Phosphorylcholine Derivatives
• Mol File: 103634-10-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Methanol, Tetrahydrofuran
• CAS DataBase Reference: [R-(Z)]-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt(CAS DataBase Reference)
• NIST Chemistry Reference: [R-(Z)]-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt(103634-10-2)
• EPA Substance Registry System: [R-(Z)]-4-Hydroxy-N,N,N-triMethyl-9-oxo-7-[(triphenylMethoxy)Methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aMiniuM 4-Oxide Inner Salt(103634-10-2)

Safety Data

• Hazardous Substances Data: 103634-10-2(Hazardous Substances Data)

Usage

Chemical Properties

Pale Yellow Solid

Uses

Intermediate in the synthesis of glycerophospholipids act as regulators of various enzyme activities

Upstream product

• 112-80-1 cis-Octadecenoic acid 
• 76-83-5 trityl chloride 
• 28319-77-9 L-glycero-3-phosphorylcholine 
• 103675-56-5 1-O-trityl-sn-glycero-3-phosphocholine 
• 64833-92-7 oleoylimidazole 

Downstream Products

• 6753-55-5 2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine 

Relevant articles and documents

Synthesis of phosphatidylcholines containing ricinoleic acid

1,2-Diricinoleoyl- and 1-ricinoleoyl-2-oleoyl-sn-glycero-3-phosphocholine were synthesised with good yields. The synthesis started with the preparation of ricinoleic acid from castor oil. The choice of a suitable agent to protect the -OH group of ricinoleic acid was a key factor to afford the final products. Several protecting groups were assayed but only β-methoxyethoxymethyl chloride (MEMCl) and 2,2,2-trichloroethyl chloroformate (TRECCl) gave reasonable yields and good optical purities of the final products. The overall yields for 1,2-diricinoleoyl-sn-glycero-3-phosphocholine and 1-ricinoleoyl-2-oleoyl-sn-glycero-3-phosphocholine were 32.1% (with respect to ricinoleic acid methyl ester using TREC as protecting group) and 10.3% (with respect to 1-trityl-glycero-3-phosphocholine), respectively.