10444-19-6

Basic information

• Product Name: 4-cyano-2-phenylbutyric acid ethyl ester
• Synonyms: 4-cyano-2-phenylbutyric acid ethyl ester
• CAS NO: 10444-19-6
• Molecular Weight: 217.268
• Mol File: 10444-19-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-cyano-2-phenylbutyric acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-cyano-2-phenylbutyric acid ethyl ester(10444-19-6)
• EPA Substance Registry System: 4-cyano-2-phenylbutyric acid ethyl ester(10444-19-6)

Safety Data

• Hazardous Substances Data: 10444-19-6(Hazardous Substances Data)

Upstream product

• 101-97-3 Ethyl 2-phenylethanoate 
• 107-13-1 acrylonitrile 
• 83-13-6 diethyl 2-phenylmalonate 
• 17838-69-6 ethyl 3-oxo-2-phenylpropanoate 
• 10444-14-1 Diethyl 2-(2-cyanoethyl)-2-phenylmalonate 

Downstream Products

• 51551-56-5 (RS)-3-phenylpiperidin-2-one 
• 14149-34-9 3-phenyl-2,6-piperidine-dione 
• 10444-31-2 2-hydroxy-5-phenyltetrahydropyran 
• 10444-25-4 4-Phenyl-5-hydroxy-pentansaeurenitril 

Relevant articles and documents

C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION

This invention provides Degronimers that have carbon-linked E3 Ubiquitin Ligase targeting moieties (Degrons), which can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation.

New methods for the selective reduction of disubstituted malonates to the corresponding hydroxy-ester derivatives

The reduction of alkylphenylmalonates and dialkylmalonates with LiAl(O- t-Bu)3H proceeds with selective reduction of one of the ester functionalities to provide the hydroxy-ester derivatives in good yields.