1046494-86-3

Basic information

• Product Name: 2-(4-formylphenoxymethyl)benzoic acid
• Synonyms: 2-(4-formylphenoxymethyl)benzoic acid
• CAS NO: 1046494-86-3
• Molecular Weight: 256.258
• Mol File: 1046494-86-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-formylphenoxymethyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-formylphenoxymethyl)benzoic acid(1046494-86-3)
• EPA Substance Registry System: 2-(4-formylphenoxymethyl)benzoic acid(1046494-86-3)

Safety Data

• Hazardous Substances Data: 1046494-86-3(Hazardous Substances Data)

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 2417-73-4 methyl 2-bromomethylbenzoate 
• 1046494-85-2 methyl 2-(4-formylphenoxymethyl)benzoate 

Downstream Products

• 1296210-21-3 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(10-aminodecylaminomethyl)phenoxymethyl]benzamide 
• 1296210-20-2 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(9-aminononylaminomethyl)phenoxymethyl]benzamide 
• 1296210-19-9 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(8-aminooctylaminomethyl)phenoxymethyl]benzamide 
• 1296210-18-8 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(7-aminoheptylaminomethyl)phenoxymethyl]benzamide 
• 1296210-17-7 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(6-aminohexylaminomethyl)phenoxymethyl]benzamide 
• 1296210-16-6 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(5-aminopentylaminomethyl)phenoxymethyl]benzamide 
• 1296210-15-5 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(4-aminobutylaminomethyl)phenoxymethyl]benzamide 
• 1296210-14-4 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(3-aminopropylaminomethyl)phenoxymethyl]benzamide 
• 1296210-13-3 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(decylaminomethyl)phenoxymethyl]benzamide 
• 1296210-12-2 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(nonylaminomethyl)phenoxymethyl]benzamide 
• 1296210-11-1 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(octylaminomethyl)phenoxymethyl]benzamide 
• 1296210-10-0 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(heptylaminomethyl)phenoxymethyl]benzamide 
• 1296210-09-7 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(hexylaminomethyl)phenoxymethyl]benzamide 
• 1296210-08-6 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(pentylaminomethyl)phenoxymethyl]benzamide 

Relevant articles and documents

Synthesis and pharmacological evaluation of bivalent antagonists of the nociceptin opioid receptor

Bivalent ligands constituted by two identical pharmacophores structurally related to the Nociceptin Opioid Receptor (NOPr) antagonist JTC-801 were synthesized and their binding affinities for NOPr were evaluated. The novel ligands are formed by two modifi

Dibenzoxepinone hydroxylamines and hydroxamic acids: Dual inhibitors of cyclooxygenase and 5-lipoxygenase with potent topical antiinflammatory activity

Hydroxylamine and hydroxamic acid derivatives of a known nonsteroidal antiinflammatory dibenzoxepine series display both cyclooxygenase (CO) and 5- lipoxygenase (5-LO) inhibitory properties. Many of these new dual CO/5-LO inhibitors also exhibit potent topical antiinflammatory activity in the arachidonic acid-induced murine ear edema model. On the basis of their promising profile of in vitro and in vivo activities, hydroxamic acids 24h, 3-(6,11-dihydro-11-oxodibenz[b,e]oxepin-2-yl)-N-hydroxy-N-methylpropanamide (HP 977), and 25, 3-(6,11-dihydrodibenz[b,e]oxepin-2-yl)-N-hydroxy-N- methylpropanamide (P10294), were selected as developmental candidates for the topical treatment of inflammatory skin disorders.