1296210-21-3Relevant articles and documents
Synthesis and pharmacological evaluation of bivalent antagonists of the nociceptin opioid receptor
Del Giudice, Maria Rosaria,Borioni, Anna,Bastanzio, Giuditta,Sbraccia, Maria,Mustazza, Carlo,Sestili, Isabella
, p. 1207 - 1221 (2011/04/23)
Bivalent ligands constituted by two identical pharmacophores structurally related to the Nociceptin Opioid Receptor (NOPr) antagonist JTC-801 were synthesized and their binding affinities for NOPr were evaluated. The novel ligands are formed by two modifi