104738-98-9

Basic information

• Product Name: Dibenzyl-[3-((R)-5-tert-butyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-propyl]-amine
• CAS NO: 104738-98-9
• Molecular Weight: 435.61
• Mol File: 104738-98-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Dibenzyl-[3-((R)-5-tert-butyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-propyl]-amine(CAS DataBase Reference)
• NIST Chemistry Reference: Dibenzyl-[3-((R)-5-tert-butyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-propyl]-amine(104738-98-9)
• EPA Substance Registry System: Dibenzyl-[3-((R)-5-tert-butyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-propyl]-amine(104738-98-9)

Safety Data

• Hazardous Substances Data: 104738-98-9(Hazardous Substances Data)

Upstream product

• 98346-35-1 N,N-dibenzyl-N-(3-bromopropyl)amine 
• 409110-61-8 2-tert-Butyl-3,6-dimethoxy-2,5-dihydro-pyrazine 

Downstream Products

• 3850-31-5 methyl tert-leucinate 
• 104738-96-7 methyl (2S)-2-amino-5-(dibenzylamino)pentanoate 
• 104738-96-7 (R)-2-Amino-5-dibenzylamino-pentanoic acid methyl ester 

Relevant articles and documents

Asymmetric Syntheses via Heterocyclic Intermediates, XXXI.- Asymmetric Synthesis of Various Non-Proteinogenic Amino Acid Methyl Esters (Functionalized in the Carbon Chain) and Amino Acids by the Bislactim Ether Method

The lithiated bislactim ethers 5, 10, 12, and 23 were alkylated with a variety of alkylating agents 6 to give the alkylated bislactim ethers 7, 11, 13, and 24 with a high degree of asymmetric induction (up to 99percent).Upon hydrolysis these furnished the optically active amino acid methyl esters of type 8, 14, or 25.Some of these amino acid esters were further hydrolyzed to yield the amino acids.