3850-31-5

Basic information

• Product Name: METHYL 2-AMINO-3,3-DIMETHYLBUTANOATE
• Synonyms: METHYL 2-AMINO-3,3-DIMETHYLBUTANOATE;VALINE, 3-METHYL-, METHYL ESTER
• CAS NO: 3850-31-5
• Molecular Formula: C₇H₁₅NO₂
• Molecular Weight: 145.2
• Mol File: 3850-31-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 163.1±13.0 °C(Predicted)
• Appearance: /
• Density: 0.957±0.06 g/cm3(Predicted)
• PKA: 8.01±0.37(Predicted)
• CAS DataBase Reference: METHYL 2-AMINO-3,3-DIMETHYLBUTANOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-AMINO-3,3-DIMETHYLBUTANOATE(3850-31-5)
• EPA Substance Registry System: METHYL 2-AMINO-3,3-DIMETHYLBUTANOATE(3850-31-5)

Safety Data

• Hazardous Substances Data: 3850-31-5(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 33105-81-6 2-amino-3,3-dimethylbutanoic acid 
• 38941-46-7 methyl trimethylpyruvate 
• 104738-98-9 Dibenzyl-[3-((R)-5-tert-butyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-propyl]-amine 
• 104738-97-8 Dibenzyl-[2-((R)-5-tert-butyl-3,6-dimethoxy-2,5-dihydro-pyrazin-2-yl)-ethyl]-amine 
• 122889-17-2 3,3-Dimethyl-2-[(Z)-trimethylsilanyl-imino]-butyric acid methyl ester 
• 186581-53-3 diazomethane 
• 62965-34-8 Trimethylpyruvic acid oxime 

Downstream Products

• 1162665-53-3 C₁₆H₂₈N₂O₃ 
• 522639-06-1 2-benzoylamino-2-bromo-3,3-dimethyl-butyric acid methyl ester 

Relevant articles and documents

Design of radical-resistant amino acid residues: A combined theoretical and experimental investigation

Ab initio calculations have been used to design radical -resistant amino acid residues. Optimized structures of free and protected amino acids and their corresponding β-carbon-centered radicals were determined with B3-LYP/6-31G(d). Single-point RMP2/6-31G

Preparation of α-(N-Trimethylsilyl)imino Esters and Their Use ih the Synthesis of α-Amino Esters and 2-Alkoxycarbonylimidazol-4(2H)-ones

The reaction of α-keto esters with lithium 1,1,1,3,3,3-hexamethyldisilazanide afforded α-(N-trimethylsilyl)imino esters in good yields, which were reduced to the corresponding α-amino esters by reducing agents such as NaBH3CN. α-(N-Trimethylsilyl)imino esters were treated with methanol to afford 2-alkoxycarbonylimidazole-4(2H)-ones via dimerization of the intermediate α-imino esters.