104830-35-5

Basic information

• Product Name: p-toluenesulfonamidosuccinic acid diethyl ester
• Synonyms: p-toluenesulfonamidosuccinic acid diethyl ester
• CAS NO: 104830-35-5
• Molecular Weight: 343.401
• Mol File: 104830-35-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: p-toluenesulfonamidosuccinic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: p-toluenesulfonamidosuccinic acid diethyl ester(104830-35-5)
• EPA Substance Registry System: p-toluenesulfonamidosuccinic acid diethyl ester(104830-35-5)

Safety Data

• Hazardous Substances Data: 104830-35-5(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 64-17-5 ethanol 
• 190773-33-2 p-CH₃C₆H₄SO₂NHCH(CH₂COOH)COOH 
• 4816-82-4 N-[(4-methylphenyl)-sulfonyl]-L-aspartic acid 
• 13552-87-9 L-aspartic acid diethyl ester 
• 104830-33-3 C₁₅H₂₀N₂O₇S 
• 43101-48-0 DL-aspartic acid diethyl ester 
• 70-55-3 toluene-4-sulfonamide 
• 623-91-6 diethyl Fumarate 

Relevant articles and documents

Ligand-Enabled Copper-Catalyzed N-Alkynylation of Sulfonamide with Alkynyl Benziodoxolone: Synthesis of Amino Acid-Derived Ynamide

Ynamides are versatile building blocks in organic synthesis. However, the synthesis of amino acid-derived ynamides is difficult but in high demand. Herein, we disclose the copper-catalyzed Csp-N coupling of sulfonamide, including amino acid and peptide derivatives, to give ynamides by using alkynyl benziodoxolones with broad functional group tolerance under mild reaction conditions. The electron-rich bipyridine as a ligand and ethanol as solvent were used for the success of this reaction. The usefulness of the obtained amino acid-derived ynamide as building block was showcased by further derivatization to unique amino acid derivatives. A control experiment to elucidate the mechanistic insight was also described.

Ultrasound-promoted solvent-free aza-Michael addition of p-toluenesulfonamide to fumaric esters by potassium carbonate: Synthesis of p-toluenesulfonamide derivatives

An efficient, mild, inexpensive and eco-friendly protocol for the synthesis of p-toluenesulfonamide derivatives by aza-Michael addition reaction of p-toluenesulfonamide to fumaric esters using potassium carbonate under ultrasound irradiation was developed

REGIOSELECTIVE TRANSFORMATION OF UNSYMMETRICAL BIS(N-NITROSOSULFONAMIDES) LEADING TO OPTICALLY ACTIVE CYCLIC IMINO ACID DERIVATIVES FROM L-LYSINE AND L-ORNITHINE

Chiral cyclic imino acid derivatives were prepared from unsymmetrical bis(N-nitrososulfonamides) of diaminocarboxylic acids, L-lysine and L-ornithine, in good yields through kinetically controlled regioselective N-nitrososulfonamide-sulfonate rearrangement.