107933-56-2

Basic information

• Product Name: 5-phenyl-2-vinyl-2H-tetrazole
• Synonyms: 5-phenyl-2-vinyl-2H-tetrazole
• CAS NO: 107933-56-2
• Molecular Weight: 172.189
• Mol File: 107933-56-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-phenyl-2-vinyl-2H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-phenyl-2-vinyl-2H-tetrazole(107933-56-2)
• EPA Substance Registry System: 5-phenyl-2-vinyl-2H-tetrazole(107933-56-2)

Safety Data

• Hazardous Substances Data: 107933-56-2(Hazardous Substances Data)

Upstream product

• 108-05-4 vinyl acetate 
• 18039-42-4 5-Phenyl-1H-tetrazole 
• 2758-06-7 (2-bromoethyl)trimethylammonium bromide 
• 64073-60-5 potassium salt of 5-phenyltetrazole 
• 106-93-4 ethylene dibromide 
• 1219537-19-5 trimethyl-2-(5-phenyl-2H-tetrazol-2-yl)ethylammonium bromide 
• 93742-43-9 2-(β-hydroxyethyl)-5-phenyltetrazole 
• 131727-62-3 1-chloro-2-(5-phenyltetrazol-2-yl)ethane 

Downstream Products

• 1299471-90-1 5-phenyl-2-[2-(E)-(2-fluorophenyl)ethenyl]tetrazole 
• 1416563-08-0 5-phenyl-2-[(E)-2-phenylethenyl]-2H-tetrazole 
• 2458-26-6 3-phenylpyrazole 

Relevant articles and documents

One-pot regioselective vinylation of tetrazoles: preparation of 5-substituted 2-vinyl-2H-tetrazoles

The one-pot regioselective preparation of 5-aryl/alkyl-2-vinyl-2H-tetrazoles from 5-substituted tetrazoles via a very simple procedure using 1,2-dibromoethane and triethylamine without the need of any catalyst is described. The mechanism of this reaction is also discussed.

SYNTHESIS OF FUNCTIONALLY SUBSTITUTED N-VINYLTETRAZOLES

5-Alkyl- and 5-aryl-N-vinyltetrazoles (II) are formed during vinyl exchange between 5-substituted tetrazoles (I) and vinyl acetate in the presence of the copper acetate-boron trifluoride etherate catalytic system.The direction of vinylation depends on steric effects and on the electronic nature of the substituents at position 5 of the tetrazole ring.A series of functionally substituted 2-vinyltetrazoles were obtained by nucleophilic substitution of the chlorine in 2-vinyl-5-chloromethyltetrazole.