1083-27-8Relevant articles and documents
Inhibition of estrone sulfatase (ES) by alkyl and cycloalkyl ester derivatives of 4-[(aminosulfonyl)oxy] benzoic acid
Patel, Chirag K.,Owen, Caroline P.,Ahmed, Sabbir
, p. 605 - 609 (2004)
In our search for potent inhibitors of the enzyme estrone sulfatase (ES), we have undertaken the synthesis and biochemical evaluation of a range of esters of 4-[(aminosulfonyl)oxy] benzoic acid. The results of the study show that the synthesised compounds possess potent inhibitory activity, indeed the cyclooctyl derivative was found to be more potent than 667-COUMATE, which is currently undergoing clinical trials.
Iron-catalyzed C[sbnd]C bond activation/C[sbnd]O bond formation: Direct conversion of ketones to esters
Arzumanyan, Ashot V.
, p. 4667 - 4671 (2017)
The iron-catalyzed oxidative activation of the (O)C[sbnd]C bond in ketones has been developed. This method enables direct synthesis of esters by the reaction between ketones and alcohols via conversion of the (O)C[sbnd]C bond to the (O)C[sbnd]O bond. The
Insect repellents (by machine translation)
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Paragraph 0030, (2019/06/07)
[Problem] excellent safety, provides effective insect repellent insect repellent. (1) Formula [solution]4 - Hydroxybenzoic acid hexyl represented comprises an insect repellent. [Drawing] no (by machine translation)
METHOD FOR PRODUCING HEXYL 4-HYDROXYBENZOATE
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Paragraph 0062; 0063; 0064; 0065; 0066; 0067; 0068-0070, (2018/07/28)
PROBLEM TO BE SOLVED: To provide a production method that makes it possible to obtain hexyl 4-hydroxybenzoate with excellent productivity, reduced by-products, and high yield, and a production method that makes it possible to obtain high-purity hexyl 4-hydroxybenzoate. SOLUTION: The present invention provides a method for producing hexyl 4-hydroxybenzoate represented by formula (1), including the step of making a reaction occur between hexyl 4-hydroxybenzoate of 1 molar equivalent and 1-hexanol of 0.8-3.0 molar equivalents in the presence of an acid catalyst. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT