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1083-27-8

Basic Information
CAS No.: 1083-27-8
Name: HEXYL 4-HYDROXYBENZOATE
Article Data: 15
Molecular Structure:
Molecular Structure of 1083-27-8 (HEXYL 4-HYDROXYBENZOATE)
Formula: C13H18 O3
Molecular Weight: 222.284
Synonyms: Benzoicacid, p-hydroxy-, hexyl ester (6CI,7CI,8CI); Hexyl 4-hydroxybenzoate; Hexylp-hydroxybenzoate; Hexylparaben; UA 12690; n-Hexyl 4-hydroxybenzoate
Density: 1.067g/cm3
Melting Point: 53oC
Boiling Point: 339°C at 760 mmHg
Flash Point: 138.5°C
Solubility: 137.6mg/L(25 oC)
Risk Codes: R36/37/38
PSA: 46.53000
LogP: 3.12930
Synthetic route
99-93-4

4-Hydroxyacetophenone

111-27-3

hexan-1-ol

1083-27-8

hexyl paraben

Conditions
ConditionsYield
With iron(III) chloride; ammonium persulfate In tetrachloromethane; 1,2-dichloro-ethane at 120℃; for 15h;76%
123-08-0

4-hydroxy-benzaldehyde

80033-60-9

1-(tert-butyldimethylsilyl)oxyhexane

1083-27-8

hexyl paraben

Conditions
ConditionsYield
With [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; Selectfluor In acetonitrile at 20℃; for 7h; Inert atmosphere; Irradiation;73%
111-27-3

hexan-1-ol

99-96-7

4-hydroxy-benzoic acid

1083-27-8

hexyl paraben

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In tetrahydrofuran for 20h;66%
With sulfuric acid In toluene for 4h; Heating;53.2%
With hydrogenchloride at 150℃;

(E)-1,3-diethyl-2-(hexyltriaz-2-en-1-ylidene)-2,3-dihydro-1H-imidazole

99-96-7

4-hydroxy-benzoic acid

A

111222-69-6

n-hexyl 4-(hexyloxy)benzoate

B

1083-27-8

hexyl paraben

C

C7H13N3

Conditions
ConditionsYield
In methanol; dichloromethane at 20℃; for 4h; Inert atmosphere;A 12%
B 51%
C n/a
111-25-1

1-bromo-hexane

99-96-7

4-hydroxy-benzoic acid

A

1142-39-8

para-hexyloxybenzoic acid

B

1083-27-8

hexyl paraben

Conditions
ConditionsYield
With PEG 200; potassium hydroxide at 80℃; for 2h; Title compound not separated from byproducts;A 83 % Spectr.
B 7 % Spectr.
With PEG 200; potassium hydroxide In 1,4-dioxane at 80℃; for 2h; Title compound not separated from byproducts;A 73 % Spectr.
B 11 % Spectr.
111-25-1

1-bromo-hexane

1083-27-8

hexyl paraben

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: durch 6-taegiges Kochen
2: hydrogen chloride / 150 °C
View Scheme
Multi-step reaction with 2 steps
2: hydrogen chloride / 150 °C
View Scheme

1,2,4-tris(4-chloroformylphenyloxycarbonyl)benzene

1083-27-8

hexyl paraben

1194090-79-3

C69H66O18

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 5h;88%
With triethylamine In dichloromethane at 20℃; for 5h;
1083-27-8

hexyl paraben

hexyl 4-[(aminosulphonyl)oxy]benzoate

Conditions
ConditionsYield
With sulphamoyl chloride; sodium hydride In N,N-dimethyl-formamide; toluene for 10h; Heating;35.4%
Stage #1: hexyl paraben With sodium hydride In N,N-dimethyl-formamide at 0℃;
Stage #2: With sulphamoyl chloride In N,N-dimethyl-formamide; toluene
Stage #1: hexyl paraben With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.5h;
Stage #2: With sulphamoyl chloride In N,N-dimethyl-formamide; toluene for 10h;
1083-27-8

hexyl paraben

phosphoric acid tris-(4-hexyloxycarbonyl-phenyl ester)

Conditions
ConditionsYield
With trichlorophosphate
1083-27-8

hexyl paraben

100-35-6

2-(diethylamino)ethyl chloride

4-(2-diethylamino-ethoxy)-benzoic acid hexyl ester

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