1089333-62-9

Basic information

• Product Name: 4-(5-methylthiophen-2-yl)benzaldehyde
• Synonyms: 4-(5-methylthiophen-2-yl)benzaldehyde
• CAS NO: 1089333-62-9
• Molecular Weight: 202.277
• Mol File: 1089333-62-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-(5-methylthiophen-2-yl)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-methylthiophen-2-yl)benzaldehyde(1089333-62-9)
• EPA Substance Registry System: 4-(5-methylthiophen-2-yl)benzaldehyde(1089333-62-9)

Safety Data

• Hazardous Substances Data: 1089333-62-9(Hazardous Substances Data)

Upstream product

• 554-14-3 2-Methylthiophene 
• 104-88-1 4-chlorobenzaldehyde 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 550348-58-8 1-[5-(4-(1,3-dioxolan-2-yl)phenyl)-2-methyl-3-thienyl]-2-(2-methyl-5-phenyl-3-thienyl)hexafluorocyclopentene 
• 550348-57-7 3-bromo-5-(4-(1,3-dioxolan-2-yl)phenyl)-2-methylthiophene 
• 550348-56-6 4-(4-bromo-5-methylthiophen-2-yl)benzaldehyde 
• 386217-82-9 1-(2-methyl-5-phenyl-3-thienyl)-2-(2-methyl-5-(4-formylphenyl)-3-thienyl)hexafluorocyclopentene 
• 1375061-65-6 C₃₄H₂₄F₆O₂S₃ 
• 1344734-19-5 C₃₅H₂₄F₆O₂S₂ 
• 1344734-18-4 1-[2-methyl-5-(4-formylphenyl)-3-thienyl]-2-(2-methyl-3-benzothiophenyl) perfluorocyclopentene 
• 1344734-12-8 C₄₁H₂₈F₆O₂S₃ 
• 1344734-09-3 C₃₂H₂₀F₆OS₃ 

Relevant articles and documents

BENZIMIDAZOLE COMPOUNDS AND USE THEREOF FOR TREATING ALZHEIMER'S DISEASE OR HUNTINGTON'S DISEASE

Benzimidazole compounds of formula (I), shown below, are disclosed. The compounds are potent human glutaminyl cyclase inhibitors. Also disclosed is a pharmaceutical composition containing one of these compounds and a pharmaceutical acceptable carrier, as well as a method of treating Alzheimer's disease or Huntington's disease by administering to a subject in need thereof an effective amount of such a compound.

Well-Defined Palladium N-Heterocyclic Carbene Complexes: Direct C-H Bond Arylation of Heteroarenes

A series of palladium N-heterocyclic carbene (NHC) complexes of type trans-{(NHC)PdCl2L} (L = C5H5N, 3-ClC5H4N, and PPh3) (3-5) have been developed as efficient precatalysts for direct C-H bond arylation of various heteroarenes. In particular, an in situ generated new NHC ligand derived from {1,3-di-(2,6-diethylphenyl)acenaphtho[1,2-d] imidazolium} chloride (2) is used for the stabilization of the palladium metal center. Among the screened palladium precatalysts (3-5), the most active PEPPSI themed complex (3) was successfully employed toward direct C-H bond arylation of various heteroarenes and aryl bromides. A range of functional groups on aryl bromides as well as on heteroarenes sustained throughout the standard reaction conditions for easy access of various arylated heterocyclic compounds. Significantly, the utility of the protocol was demonstrated by the effective synthesis of a precursor of raloxifene, a selective estrogen receptor modulator.

Efficient Pd-catalyzed direct arylations of heterocycles with unreactive and hindered aryl chlorides

A highly electron-rich Pd complex can efficiently catalyze the direct arylation of heteroaromatics with unreactive and sterically congested aryl chlorides.