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1092521-65-7

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1092521-65-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1092521-65-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,2,5,2 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1092521-65:
(9*1)+(8*0)+(7*9)+(6*2)+(5*5)+(4*2)+(3*1)+(2*6)+(1*5)=137
137 % 10 = 7
So 1092521-65-7 is a valid CAS Registry Number.

1092521-65-7Downstream Products

1092521-65-7Relevant articles and documents

Identification of KD5170: A novel mercaptoketone-based histone deacetylase inhibitor

Payne, Joseph E.,Bonnefous, Celine,Hassig, Christian A.,Symons, Kent T.,Guo, Xin,Nguyen, Phan-Manh,Annable, Tami,Wash, Paul L.,Hoffman, Timothy Z.,Rao, Tadimeti S.,Shiau, Andrew K.,Malecha, James W.,Noble, Stewart A.,Hager, Jeffrey H.,Smith, Nicholas D.

scheme or table, p. 6093 - 6096 (2009/07/18)

We report the identification of KD5170, a potent mercaptoketone-based Class I and II-histone deacetylase inhibitor that demonstrates broad spectrum cytotoxic activity against a range of human tumor-derived cell lines. KD5170 exhibits robust and sustained histone H3 hyperacetylation in HCT-116 xenograft tumors following single oral or iv dose and inhibition of tumor growth following chronic dosing.

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