112107-56-9

Basic information

• Product Name: 4H-Imidazol-4-one, 1,5-dihydro-5-hydroxy-2-phenyl-5-(trifluoromethyl)-
• CAS NO: 112107-56-9
• Molecular Formula: C10H7F3N2O2
• Molecular Weight: 244.173
• Mol File: 112107-56-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4H-Imidazol-4-one, 1,5-dihydro-5-hydroxy-2-phenyl-5-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Imidazol-4-one, 1,5-dihydro-5-hydroxy-2-phenyl-5-(trifluoromethyl)-(112107-56-9)
• EPA Substance Registry System: 4H-Imidazol-4-one, 1,5-dihydro-5-hydroxy-2-phenyl-5-(trifluoromethyl)-(112107-56-9)

Safety Data

• Hazardous Substances Data: 112107-56-9(Hazardous Substances Data)

Upstream product

• 26728-43-8 ethyl 3,3,3-trifluoropyruvate ethylhemiketal 
• 1670-14-0 benzamidine monohydrochloride 
• 13089-11-7 methyl 3,3,3-trifluoropyruvate 
• 618-39-3 benzamidin 

Downstream Products

• 153998-72-2 4-chloro-2-phenyl-4-trifluoromethyl-2-imidazolin-5-one 

Relevant articles and documents

Reactions of 3,3,3-Trifluoropyruvates with Amidines - New Trifluoromethyl Substituted Heterocyclic "Building Blocks"

4-Hydroxy-4-trifluoromethyl-2-imidazolin-5-ones are obtained in good yields upon reaction of 3,3,3-trifluoropyruvates with amidines.Subsequent treatment of these heterocycles with thionyl chloride gives 4-chloro-4-trifluoromethyl-2-imidazolin-5-ones which proved to be versatile trifluoromethyl substituted building blocks.Substitution of chloride is feasible with a variety of hetero and carbon nucleophiles.Ring expansion with diazo compounds affords trifluoromethyl substituted pyrimidines. - Keywords. 3,3,3-Trifluoropyruvates; Amidines; 4-Trifluoromethyl-2-imidazolin-5-ones; Trifluoromethyl substituted pyrimidines.