112257-12-2Relevant articles and documents
A ruthenium(ii) complex-cyanine energy transfer scaffold based luminescence probe for ratiometric detection and imaging of mitochondrial peroxynitrite
Zhang, Wenzhu,Liu, Yi,Gao, Quankun,Liu, Chaolong,Song, Bo,Zhang, Run,Yuan, Jingli
, p. 13698 - 13701 (2018)
A novel ruthenium(ii) complex-cyanine energy transfer scaffold has been established for the development of a ratiometric luminescence probe for ONOO- detection. The probe, Ru-Cy5, is localized in mitochondria of live cells, allowing ratiometric sensing and imaging of ONOO- therein.
UDP GLYCOSYLTRANSFERASE INHIBITORS AND METHODS OF USE
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Paragraph 1381; 1382, (2020/04/24)
Described herein is a compound of Formula (I), and pharmaceutically acceptable salts thereof. Also described herein are compositions and the use of such compositions in methods of treating a variety of diseases and conditions, in particular Krabbe's Disease (KD) and Metachromatic leukodystrophy (MLD).
FUSED RING HETEROARYL COMPOUNDS AND THEIR USE AS TRK INHIBITORS
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Paragraph 0510; 0511, (2016/07/05)
The disclosure provides novel chemical compounds represented by Formula I or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof. The compounds can be used as an inhibitor of Trk and are useful in the treatment of pain, cancer, inflammation, neurodegenerative disease and certain infectious diseases. In some compounds of Formula I, Q is —CH═CR3C(O)NR4R5, —C≡CC(O)NR4R5, or
