890153-36-3

Basic information

• Product Name: 1-triphenylphosphoranylidenemethylcarbonyl-4-tert-butoxycarbonyl-piperazine
• CAS NO: 890153-36-3
• Molecular Weight: 488.566
• Mol File: 890153-36-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-triphenylphosphoranylidenemethylcarbonyl-4-tert-butoxycarbonyl-piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-triphenylphosphoranylidenemethylcarbonyl-4-tert-butoxycarbonyl-piperazine(890153-36-3)
• EPA Substance Registry System: 1-triphenylphosphoranylidenemethylcarbonyl-4-tert-butoxycarbonyl-piperazine(890153-36-3)

Safety Data

• Hazardous Substances Data: 890153-36-3(Hazardous Substances Data)

Upstream product

• 603-35-0 triphenylphosphine 
• 112257-12-2 4-(2-bromoacetyl)piperazine-1-carboxylic acid tert butyl ester 

Relevant articles and documents

PIPERAZINE DERIVATIVE

A compound represented by the formula (I): [wherein R1 represents C3-9 branched alkyl; R2 represents, e.g., linear or branched, C2-9 alkyl optionally substituted by halogen, etc.; and X represents oxygen, etc.] (provided that the following cases are excluded: the case where R1 is tert-butyl, R2 is 2-methylpropyl, phenyl, tert-butyl, benzyl, or cyclohexyl, and X is oxygen and the case where R1 is tert-butyl, R2 is adamantly, neopentyl, or cyclohexylethenyl, and R3 is a single bond); or a pharmaceutically acceptable salt of the compound. The compound and salt have inhibitory activity against metabotropic glutamate receptor 1. They are hence useful for the treatment of diseases such as convulsion, acute pain, inflammatory pain, chronic pain, psychofunctional disorders including schizophrenia, and anxiety.