1130037-51-2

Basic information

• Product Name: [carboxy-14C]4-(2-chloro-5-fluorobenzoylamino)-3-methoxybenzoic acid
• CAS NO: 1130037-51-2
• Molecular Weight: 325.697
• Mol File: 1130037-51-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [carboxy-14C]4-(2-chloro-5-fluorobenzoylamino)-3-methoxybenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [carboxy-14C]4-(2-chloro-5-fluorobenzoylamino)-3-methoxybenzoic acid(1130037-51-2)
• EPA Substance Registry System: [carboxy-14C]4-(2-chloro-5-fluorobenzoylamino)-3-methoxybenzoic acid(1130037-51-2)

Safety Data

• Hazardous Substances Data: 1130037-51-2(Hazardous Substances Data)

Upstream product

• 21900-51-6 2-chloro-5-fluorobenzoyl chloride 

Relevant articles and documents

Synthesis of [2H, 13C] and [14C] labeled vasopressin V1a/V2 receptor antagonist RWJ-676070 and its stable labeled N-des-benzoyl metabolite

Stable isotope-labeled ([13C2, D3]) and carbon 14-labeled vasopressin receptor antagonist RWJ-676070, a spirobenzazepine amide, were prepared in separate syntheses for use in drug metabolism studies. The stable isotopically labeled sample was prepared starting from [ 13C2, D6]dimethyl sulfate and [ 13C]copper (I) cyanide in nine steps with a 14% overall isotopic yield. The 14C label was introduced in five steps starting from [14C]potassium cyanide to provide material having a specific activity of 58 mCi/mmol (2.15 GBq/mmol). Selective hydrolysis of the metabolically labile amide bond in [13C2, D3]RWJ-676070 gave the corresponding labeled metabolite in one step. Copyright