113240-61-2

Basic information

• Product Name: Hexanoic acid, 5-hydroxy-3-oxo-6-(triphenylmethoxy)-, 1,1-dimethylethyl ester, (S)-
• CAS NO: 113240-61-2
• Molecular Formula: C29H32O5
• Molecular Weight: 460.57
• Mol File: 113240-61-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Hexanoic acid, 5-hydroxy-3-oxo-6-(triphenylmethoxy)-, 1,1-dimethylethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanoic acid, 5-hydroxy-3-oxo-6-(triphenylmethoxy)-, 1,1-dimethylethyl ester, (S)-(113240-61-2)
• EPA Substance Registry System: Hexanoic acid, 5-hydroxy-3-oxo-6-(triphenylmethoxy)-, 1,1-dimethylethyl ester, (S)-(113240-61-2)

Safety Data

• Hazardous Substances Data: 113240-61-2(Hazardous Substances Data)

Usage

General Description

Hexanoic acid, 5-hydroxy-3-oxo-6-(triphenylmethoxy)-, 1,1-dimethylethyl ester, (S)- is a chemical compound commonly referred to as an ester. It is derived from hexanoic acid and has a 5-hydroxy-3-oxo-6-(triphenylmethoxy) structure. The compound is specifically in its (S)- form, indicating its stereochemistry. It exists in the form of a clear, colorless to pale yellow liquid, and it is used in various industrial applications such as in the production of perfumes, flavorings, and as a solvent in chemical reactions. Additionally, it can also be used as a precursor in the synthesis of other organic compounds.

Upstream product

• 144754-24-5 (S)-methyl 3-hydroxy-4-(trityloxy)butanoate 
• 540-88-5 acetic acid tert-butyl ester 
• 150942-98-6 t-butyl lithioacetate 
• 109-72-8 n-butyllithium 
• 131666-63-2 (S)-3-hydroxy-4-triphenylmethoxybutanenitrile 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 7440-66-6 zinc 
• 144754-24-5 methyl (R)-3-hydroxy-4-(triphenylmethyl)oxybutanoate 

Downstream Products

• 123477-30-5 1,1-Dimethylethyl (3R,5S)-3,5-di-[(1',1'-dimethylethyl)-diphenylsilyloxy]-6-oxohexanoate 
• 130852-63-0 (3S,5S)-3,5-Bis-(tert-butyl-diphenyl-silanyloxy)-6-oxo-hexanoic acid tert-butyl ester 
• 123492-49-9 1,1-Dimethylethyl (3R,5S)-3,5-di[(1-,1-dimethylethyl)diphenylsilyloxy]-6-hydroxyhexanoate 
• 129893-64-7 (3S,5S)-3,5-Bis-(tert-butyl-diphenyl-silanyloxy)-6-hydroxy-hexanoic acid tert-butyl ester 
• 123477-29-2 1,1-Dimethylethyl (3R,5S)-3,5-di-[(1',1'-dimethylethyl)-diphenylsilyloxy]-6-(triphenylmethoxy)hexanoate 
• 130852-62-9 (3S,5S)-3,5-Bis-(tert-butyl-diphenyl-silanyloxy)-6-trityloxy-hexanoic acid tert-butyl ester 
• 130852-64-1 (3R,5R)-3,5-Bis-(tert-butyl-diphenyl-silanyloxy)-6-oxo-hexanoic acid tert-butyl ester 
• 116168-28-6 (3S,5R)-3,5-Bis-(tert-butyl-diphenyl-silanyloxy)-6-oxo-hexanoic acid tert-butyl ester 
• 123492-49-9 (3R,5R)-3,5-Bis-(tert-butyl-diphenyl-silanyloxy)-6-hydroxy-hexanoic acid tert-butyl ester 
• 123492-49-9 (3S,5R)-3,5-Bis-(tert-butyl-diphenyl-silanyloxy)-6-hydroxy-hexanoic acid tert-butyl ester 
• 123477-29-2 (3R,5R)-3,5-Bis-(tert-butyl-diphenyl-silanyloxy)-6-trityloxy-hexanoic acid tert-butyl ester 
• 123477-29-2 (3S,5R)-3,5-Bis-(tert-butyl-diphenyl-silanyloxy)-6-trityloxy-hexanoic acid tert-butyl ester 
• 123477-28-1 1,1-Dimethylethyl (3R,5S)-3,5-dihydroxy-6-(triphenylmethoxy)hexanoate 
• 130852-61-8 (3S,5S)-3,5-Dihydroxy-6-trityloxy-hexanoic acid tert-butyl ester 

Relevant articles and documents

Novel boronate esters

The present invention relates to optically active boronate derivatives which are useful as intermediates for the synthesis of HMG-CoA enzyme inhibitors such as atorvastatin, cerivastatin, rosuvastatin, pitavastatin, and fluvastatin.

A Highly Stereoselective Route to the Four Stereoisomers of a Six-Carbon Synthon

The syntheses of chiral synthones 13-16 are described utilizing the chiral pool approach starting from either S- or R-malic acid.

Processes for the synthesis of diprotected R[R*,S*]-3,5-dihydroxy-6-oxohexanoate esters

Process for the synthesis of compounds of the formula STR1 in R[R*,S*] enantiomeric form, wherein each P1 is independently an hydroxy group-protecting group, and R2z is C1-4 alkyl, benzyl or allyl, comprising, as a key step when R2z is R2x, the reaction of the compound of the formula STR2 in (S) enantiomeric form with a compound of the formula to obtain a compound of the formula STR3 in (S) enantiomeric form, and, as a key step when R2z is R2y, the reaction of a compound of the formula STR4 in (S) enantioimeric form with a compound of the formula to obtain a compound of the formula STR5 in (S) enantiomeric form, wherein R2x is primary or secondary C1-4 alkyl, benzyl or allyl, R2y is C1-4 alkyl not containing an asymmetric carbon atom, and R3 ' is methyl or ethyl, processes for the synthesis of compounds of the formula STR6 comprising reacting a compound of the formula STR7 with the reaction product of a strong base and a compound of the formula STR8 optionally followed by, when R2z is allyl, cleavage of the allyl and P1 groups to obtain the corresponding compound of the formula STR9 wherein each R7 is methyl or ethyl, R is as defined in the specification, and each P1 independently and R2z are as defined above, and the compounds of the formula STR10 wherein R and each R7 are as defined above.