1134949-07-7Relevant articles and documents
Asymmetric Halocyclizations of 2-Vinylbenzyl Alcohols with Chiral FLPs
Han, Caifang,Feng, Xiangqing,Du, Haifeng
supporting information, p. 7325 - 7329 (2021/10/01)
By the use of a chiral frustrated Lewis pair (FLP) consisting of a chiral-diene-derived borane and tBu3P as the catalyst, an asymmetric halocyclization of 2-vinylbenzyl alcohols with NBS or NIS was successfully realized. A variety of optically active 1,3-dihydroisobenofuran derivatives were obtained in high yields with up to 87% ee and could be conveniently converted to other useful chiral compounds.
Rhodium(II)- or Copper(I)-Catalyzed Formal Intramolecular Carbene Insertion into Vinylic C(sp2)?H Bonds: Access to Substituted 1H-Indenes
Zhou, Qi,Li, Shichao,Zhang, Yan,Wang, Jianbo
supporting information, p. 16013 - 16017 (2017/11/27)
A rhodium(II)- or copper(I)-catalyzed formal intramolecular carbene insertion into vinylic C(sp2)?H bonds is reported herein. This method provides straightforward access to 1H-indenes with high efficiency and excellent functional-group compatibility. Mechanistically, the reaction is proposed to involve the following sequence: metal carbene formation, intramolecular nucleophilic addition of the double bond to the electron-deficient carbene carbon atom, dearomatization, and finally a 1,5-H shift.
Synthesis of 2-benzothiophene-1(3H)-thione and isothiochromene-1-thione derivatives by iodine-mediated cyclization of lithium 2-(vinyl)dithiobenzoate derivatives
Fukamachi, Shuhei,Konishi, Hisatoshi,Kobayashi, Kazuhiro
experimental part, p. 169 - 176 (2009/05/07)
Successive treatment of α-substituted 2-bromostyrenes with butyllithium and carbon disulfide generates lithium 2-(vinyl)dithiobenzoates, which are then allowed to react with iodine to give 3-substituted 3-iodomethyl-2-benzothiophene-1(3H)-thiones and/or 4
