1135-67-7

Basic information

• Product Name: 1-PHENYL-1-CYCLOHEXANECARBOXYLIC ACID
• Synonyms: TIMTEC-BB SBB005454;RARECHEM AL BO 1130;1-PHENYL-1-CYCLOHEXANECARBOXYLIC ACID;1-PHENYLCYCLOHEXANECARBOXYLIC ACID;1-phenylcyclohexane-1-carboxylic acid;1-PHENYL-1-CYCLOHEXANECARBOXYLIC ACID 95%;1-Phenyl-1-cyclohexanecarboxylic acid,95%;1-Phenyl-1-cyclohexanecarboxylic acid, 95% 10GR
• CAS NO: 1135-67-7
• Molecular Formula: C₁₃H₁₆O₂
• Molecular Weight: 204.26
• EINECS: 214-495-8
• Mol File: 1135-67-7.mol
• Article Data: 15

Chemical Properties

• Melting Point: 119-124 °C
• Boiling Point: 302.76°C (rough estimate)
• Flash Point: 165 °C
• Appearance: Beige to brown/Powder
• Density: 1.0404 (rough estimate)
• Vapor Pressure: 1.28E-05mmHg at 25°C
• Refractive Index: 1.5180 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 4.45±0.20(Predicted)
• CAS DataBase Reference: 1-PHENYL-1-CYCLOHEXANECARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYL-1-CYCLOHEXANECARBOXYLIC ACID(1135-67-7)
• EPA Substance Registry System: 1-PHENYL-1-CYCLOHEXANECARBOXYLIC ACID(1135-67-7)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 1135-67-7(Hazardous Substances Data)

Usage

Chemical Properties

BEIGE TO BROWN POWDER

InChI:InChI=1/C13H16O2/c14-12(15)13(9-5-2-6-10-13)11-7-3-1-4-8-11/h1,3-4,7-8H,2,5-6,9-10H2,(H,14,15)/p-1

Upstream product

• 2201-23-2 1-phenyl-1-cyclohexanecarbonitrile 
• 7500-66-5 (1-bromocyclohexyl)(phenyl)methanone 
• 1135-71-3 (1-chlorocyclohexyl)(phenyl)methanone 
• 64-18-6 formic acid 
• 1589-60-2 1-phenylcyclohexanol 
• 111-24-0 1,5-dibromo-pentane 
• 40348-04-7 (Bis-trimethylsilanyloxy-methylene)-cyclohexane 
• 140-29-4 phenylacetonitrile 
• 712-50-5 Cyclohexyl phenyl ketone 
• 1115022-94-0 2-methyl-5-(1-phenylcyclohexyl)furan 
• 68692-77-3 (1-phenylcyclohexyl)methanol 
• 934-20-3 2-(hydroxymethylene)cycloheptanone 
• 502-42-1 cycloheptanone 
• 101-41-7 benzeneacetic acid methyl ester 

Downstream Products

• 827-52-1 1-phenyl-1-cyclohexane 
• 68692-77-3 (1-phenylcyclohexyl)methanol 
• 17380-78-8 methyl 1-phenyl-1-cyclohexanecarboxylate 
• 36263-71-5 6β-(1-phenyl-cyclohexanecarbonylamino)-penicillanic acid 
• 2890-42-8 1-phenylcyclohexylcarbonyl chloride 
• 2201-24-3 1-phenylcyclohexylamine 
• 3183-57-1 1-(1-phenylcyclohexyl)ethanone 
• 91958-27-9 1-(4-nitro-phenyl)-cyclohexanecarboxylic acid 
• 110397-48-3 2-Diazo-1-(1-phenyl-cyclohexyl)-ethanone 
• 914106-86-8 N-(2'-aminophenyl)-(1-(phenyl)cyclohex-1-yl)carboxamide 
• 2890-60-0 1-phenylcyclohexane-1-carboxamide 
• 17380-54-0 1-amino-2-phenyl-2,2-pentamethyleneethane 
• 5769-17-5 N-<4-Methyl-benzolsulfonyl>-N'-<1-phenyl-cyclohexyl>-harnstoff 
• 5769-26-6 N-<4-Amino-benzolsulfonyl>-N'-<1-phenyl-cyclohexyl>-harnstoff 

Relevant articles and documents

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Oxidation of Primary Alcohols and Aldehydes to Carboxylic Acids via Hydrogen Atom Transfer

The oxidation of primary alcohols and aldehydes to the corresponding carboxylic acids is a fundamental reaction in organic synthesis. In this paper, we report a new chemoselective process for the oxidation of primary alcohols and aldehydes. This metal-free reaction features a new oxidant, an easy to handle procedure, high isolated yields, and good to excellent functional group tolerance even in the presence of vulnerable secondary alcohols and tert-butanesulfinamides.

Desulfonylative Electrocarboxylation with Carbon Dioxide

Electrocarboxylation of organic halides is one of the most investigated electrochemical approaches for converting thermodynamically inert carbon dioxide (CO2) into value-added carboxylic acids. By converting organic halides into their sulfone derivatives, we have developed a highly efficient electrochemical desulfonylative carboxylation protocol. Such a strategy takes advantage of CO2as the abundant C1 building block for the facile preparation of multifunctionalized carboxylic acids, including the nonsteroidal anti-inflammatory drug ibuprofen, under mild reaction conditions.

Stereospecific Construction of Contiguous Quaternary All-Carbon Centers by Oxidative Ring Contraction

Oxidative ring contraction of cyclic α-formyl ketones was facilitated by the action of H2O2under operationally simple and environmentally benign reaction conditions. The process was highly regioselective and enables stereospecific construction of contiguous quaternary all-carbon centers from stereodefined all-substituted all-cyclic ketones. The asymmetric syntheses of (+)-cuparene and (+)-tochuinyl acetate were also successively achieved by taking advantage of this novel protocol.