114460-08-1 Usage
General Description
1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-3,4-dihydro-5H-2,3-benzodiazepine is a chemical compound that belongs to the benzodiazepine class of drugs. It is a psychoactive substance that exhibits sedative, anxiolytic, and hypnotic properties. 1-(4-AMINOPHENYL)-4-METHYL-7,8-METHYLENEDIOXY-3.4-DIHYDRO-5H-2,3-BENZODIAZEPINE is structurally related to benzodiazepines and has been studied for its potential use in the treatment of anxiety, insomnia, and other central nervous system disorders. Its chemical structure includes an aminophenyl group, a methyl group, and a methylenedioxy group, all of which contribute to its pharmacological effects. 1-(4-AMINOPHENYL)-4-METHYL-7,8-METHYLENEDIOXY-3.4-DIHYDRO-5H-2,3-BENZODIAZEPINE may have potential medical applications, but it also carries a risk of abuse and dependence and should be used with caution.
Check Digit Verification of cas no
The CAS Registry Mumber 114460-08-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,4,6 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 114460-08:
(8*1)+(7*1)+(6*4)+(5*4)+(4*6)+(3*0)+(2*0)+(1*8)=91
91 % 10 = 1
So 114460-08-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H17N3O2/c1-10-6-12-7-15-16(22-9-21-15)8-14(12)17(20-19-10)11-2-4-13(18)5-3-11/h2-5,7-8,10,19H,6,9,18H2,1H3
114460-08-1Relevant articles and documents
A simple and efficient synthesis of GYKI 52466 and GYKI 52895
Zappala, Maria,Grasso, Silvana,Micale, Nicola,Polimeni, Santina,De Micheli, Carlo
, p. 527 - 533 (2007/10/03)
The synthesis of 1-(4-aminophenyl)-4-methyl-7,8-methylene-dioxy-5H-2,3-benzodiazepine (GYKI 52466, 1), the prototype of a series of noncompetitive AMPA receptor antagonists, and its 3,4-dihydroderivative (GYKI 52895, 2) is described. The title compounds have been prepared starting from safrole through a quite effective procedure.
