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  • 1145871-52-8 Structure
  • Basic information

    1. Product Name: 6-[2-benzyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl]quinoxaline
    2. Synonyms:
    3. CAS NO:1145871-52-8
    4. Molecular Formula:
    5. Molecular Weight: 377.448
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1145871-52-8.mol
    9. Article Data: 1
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 6-[2-benzyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl]quinoxaline(CAS DataBase Reference)
    10. NIST Chemistry Reference: 6-[2-benzyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl]quinoxaline(1145871-52-8)
    11. EPA Substance Registry System: 6-[2-benzyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl]quinoxaline(1145871-52-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1145871-52-8(Hazardous Substances Data)

1145871-52-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1145871-52-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,5,8,7 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1145871-52:
(9*1)+(8*1)+(7*4)+(6*5)+(5*8)+(4*7)+(3*1)+(2*5)+(1*2)=158
158 % 10 = 8
So 1145871-52-8 is a valid CAS Registry Number.

1145871-52-8Downstream Products

1145871-52-8Relevant articles and documents

Synthesis and biological evaluation of benzenesulfonamide-substituted 4-(6-alkylpyridin-2-yl)-5-(quinoxalin-6-yl)imidazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Kim, Dae-Kee,Jung, Sun Hee,Lee, Ho Soon,Dewang, Purushottam M.

experimental part, p. 568 - 576 (2009/09/27)

A series of benzenesulfonamide-substituted 4-(6-alkylpyridin-2-yl)-5-(quinoxalin-6-yl)imidazoles (15a-l) have been synthesized and evaluated for their ALK5 inhibitory activity in cell-based luciferase reporter assays. Among them, 4-[5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-ylmethyl]b enzenesulfonamide (15b) and 4-[5-(6-ethylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-ylmethyl]be nzenesulfonamide (15c) showed more than 90% inhibition at 0.5 μM in a luciferase reporter assay using HaCaT cells transiently transfected with p3TP-luc reporter construct, but inhibited p38α MAP kinase activity only 11 and 8% at a concentration of 10 μM, respectively.

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