1147347-30-5

Basic information

• Product Name: (2S,4S)-4-(tert-butoxycarbonylamino)-4-phenylbutan-2-ol
• Synonyms: (2S,4S)-4-(tert-butoxycarbonylamino)-4-phenylbutan-2-ol
• CAS NO: 1147347-30-5
• Molecular Weight: 265.353
• Mol File: 1147347-30-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2S,4S)-4-(tert-butoxycarbonylamino)-4-phenylbutan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-4-(tert-butoxycarbonylamino)-4-phenylbutan-2-ol(1147347-30-5)
• EPA Substance Registry System: (2S,4S)-4-(tert-butoxycarbonylamino)-4-phenylbutan-2-ol(1147347-30-5)

Safety Data

• Hazardous Substances Data: 1147347-30-5(Hazardous Substances Data)

Upstream product

• 876-27-7 4-chlorophenyl acetate 
• 528586-23-4 tert-butyl ((1S)-3-oxo-1-phenylbutyl)carbamate 

Downstream Products

• 1264044-39-4 C₁₀H₁₅NO 

Relevant articles and documents

Rearrangement of 1-Phenylbutane-1,3-diamines via an azetidinium cation intermediate

Treatment of 4-amino-4-phenyl-butan-2-ol with mesyl chloride, followed by displacement with amine nucleophiles resulted in a 1,3 rearrangement via an azetidinium cation intermediate. This rearrangement has been proven to proceed via a double inversion of stereocentres at positions 1 and 3. Georg Thieme Verlag Stuttgart - New York.

Effects of methyl substituents on the activity and enantioselectivity of homobenzotetramisole-based catalysts in the kinetic resolution of alcohols

Substitution of the tetrahydropyrimidine ring in the enantioselective acyl transfer catalyst homobenzotetramisole (HBTM) 6 with methyl groups exerts a dramatic influence on its performance in the kinetic resolution of secondary alcohols. The syn-3-methyl analogue of HBTM (9a) has proved to be superior to the parent compound in terms of catalytic activity, enantioselectivity, and synthetic accessibility.