114740-40-8 Usage
General Description
O-Methyl-undecaethylene glycol is a chemical compound that belongs to the class of glycols, which are alcohols with two hydroxyl groups attached to different carbon atoms. It is a colorless and odorless liquid with a high boiling point, making it useful in various industrial applications such as in the production of plastics, resins, and as a component in antifreeze. O-Methyl-undecaethylene glycol is also employed as a solvent in the manufacturing of dyes, inks, and adhesives. Additionally, it is a key ingredient in the synthesis of specialty chemicals, pharmaceuticals, and personal care products. Its chemical structure and properties make it a versatile and widely used compound in the manufacturing of numerous consumer and industrial products.
Check Digit Verification of cas no
The CAS Registry Mumber 114740-40-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,7,4 and 0 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 114740-40:
(8*1)+(7*1)+(6*4)+(5*7)+(4*4)+(3*0)+(2*4)+(1*0)=98
98 % 10 = 8
So 114740-40-8 is a valid CAS Registry Number.
InChI:InChI=1/C23H48O12/c1-25-4-5-27-8-9-29-12-13-31-16-17-33-20-21-35-23-22-34-19-18-32-15-14-30-11-10-28-7-6-26-3-2-24/h24H,2-23H2,1H3
114740-40-8Relevant articles and documents
Monodisperse oligoethylene glycols modified Camptothecin, 10-Hydroxycamptothecin and SN38 prodrugs
Deng, Tao,Mao, Xianglan,Xiao, Yan,Yang, Zhigang,Zheng, Xing,Jiang, Zhong-Xing
, p. 581 - 584 (2019/01/04)
Camptothecin, which represents a class of natural products with high anticancer activity, suffers low water solubility which hampers its clinic application. To address this issue, monodisperse polyethylene glycols were employed to modify this class of natural products, including Camptothecin, 10-Hydroxycamptothecin, and SN38. Through selective modification with a series of monodisperse polyethylene glycols, 31 Camptothecin derivatives, including 9 ethers and 22 carbonates, were prepared using a macrocyclic sulfate-based strategy with high efficacy. Monodisperse polyethylene glycols modification provided the Camptothecin derivatives with high purity and fine-tunable water solubility. Through the physicochemical and biological assays, a few novel prodrugs with good solubility, cytotoxicity, and valuable drug release profile were identified as promising anticancer drug candidates.
