114856-91-6

Basic information

• Product Name: Carbamic acid, (1,1-dimethyl-2-oxoethyl)-, phenylmethyl ester
• CAS NO: 114856-91-6
• Molecular Formula: C12H15NO3
• Molecular Weight: 221.256
• Mol File: 114856-91-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Carbamic acid, (1,1-dimethyl-2-oxoethyl)-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (1,1-dimethyl-2-oxoethyl)-, phenylmethyl ester(114856-91-6)
• EPA Substance Registry System: Carbamic acid, (1,1-dimethyl-2-oxoethyl)-, phenylmethyl ester(114856-91-6)

Safety Data

• Hazardous Substances Data: 114856-91-6(Hazardous Substances Data)

Upstream product

• 62471-40-3 2-benzyloxycarbonylamino-2-methylpropanol 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 88282-48-8 2,5-dioxopyrrolidin-1-yl 2-(((benzyloxy)carbonyl)amino)-2-methylpropanoate 
• 15030-72-5 Z-Aib-OH 
• 875549-00-1 benzyl 1-(methoxy(methyl)amino)-2-methyl-1-oxopropan-2-ylcarbamate 
• 150391-25-6 ethyl 2-(((benzyloxy)carbonyl)amino)-2-methylpropanoate 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 128414-10-8 ((2S,3R)-2,3-Dihydroxy-1,1-dimethyl-decyl)-carbamic acid benzyl ester 
• 128414-10-8 (3,4-syn)-2--2-methylundecane-4,5-diol 
• 875549-49-8 (+)-(5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-{[4'-fluoro-2'-methoxy-5'-(propan-2-yl)-4-(trifluoromethyl)biphenyl-2-yl]methyl}-4,4-dimethyl-1,3-oxazolidin-2-one 
• 1312671-81-0 (-)-(5S)-5-[3,5-bis(trifluoromethyl)phenyl]-3-{[4'-fluoro-2'-methoxy-5'-(propan-2-yl)-4-(trifluoromethyl)biphenyl-2-yl]methyl}-4,4-dimethyl-1,3-oxazolidin-2-one 
• 1312671-75-2 5-[3,5-bis(trifluoromethyl)phenyl]-3-{[4'-fluoro-2'-methoxy-5'-(propan-2-yl)-4-(trifluoromethyl)biphenyl-2-yl]methyl}-4,4-dimethyl-1,3-oxazolidin-2-one 
• 875549-01-2 benzyl {2-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-1,1-dimethylethyl}carbamate 
• 1432584-87-6 (Z)-N-(2-(((benzyloxy)carbonyl)amino)-2-methylpropylidene)-1-(tert-butoxy)-2-methyl-1-oxopropan-2-amine oxide 
• 1352440-09-5 C₁₅H₂₁NO₆ 
• 1258834-19-3 2-(benzyloxycarbonylamino)-1-(tert-butoxycarbonyl-3-hydroxypropylamino)-2-methylpropane 
• 150391-26-7 (S)-2-((S)-2-{(2-Benzyloxycarbonylamino-2-methyl-propyl)-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-acetyl]-amino}-3-phenyl-propionylamino)-4-methyl-pentanoic acid methyl ester 
• 150391-13-2 (S)-2-{(S)-2-[(2-Amino-acetyl)-(2-benzyloxycarbonylamino-2-methyl-propyl)-amino]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methyl ester 

Relevant articles and documents

CHEMICAL COMPOUNDS

A compound of formula (I), wherein Ar1, R21, R23, R24, R25, R26, R27, A, X, Y and W are as defined herein. The compounds of the present invention are inhibitors of hematopoietic prostaglandin D synthase (H-PGDS) and can be useful in the treatment of Duchenne muscular dystrophy. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting H-PGDS activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

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