116140-87-5

Basic information

• Product Name: Butan-1-olate(1S,2R,4S,5R)-1-benzyl-2-[(S)-hydroxy-(6-methoxy-quinolin-4-yl)-methyl]-5-vinyl-1-azonia-bicyclo[2.2.2]octane;
• CAS NO: 116140-87-5
• Molecular Weight: 488.67
• Mol File: 116140-87-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Butan-1-olate(1S,2R,4S,5R)-1-benzyl-2-[(S)-hydroxy-(6-methoxy-quinolin-4-yl)-methyl]-5-vinyl-1-azonia-bicyclo[2.2.2]octane;(CAS DataBase Reference)
• NIST Chemistry Reference: Butan-1-olate(1S,2R,4S,5R)-1-benzyl-2-[(S)-hydroxy-(6-methoxy-quinolin-4-yl)-methyl]-5-vinyl-1-azonia-bicyclo[2.2.2]octane;(116140-87-5)
• EPA Substance Registry System: Butan-1-olate(1S,2R,4S,5R)-1-benzyl-2-[(S)-hydroxy-(6-methoxy-quinolin-4-yl)-methyl]-5-vinyl-1-azonia-bicyclo[2.2.2]octane;(116140-87-5)

Safety Data

• Hazardous Substances Data: 116140-87-5(Hazardous Substances Data)

Upstream product

• 77481-82-4 N-benzylquinidinium chloride 
• 2372-45-4 sodium butanolate 

Relevant articles and documents

Enantiotopic-Group Differentiation. Asymmetric Monoesterification of Malonic Acids Using Cinchona Alkaloid Derivatives

2,2-Dimethyl-5-methyl-5-phenyl-4,6-dioxo-1,3-dioxane (1) was cleaved asymmetrically, by nucleophilic attack of primary alkoxide ions, paired with N-benzylquaternary ammonium cations, derived from cinchona alkaloids, to give optically active monoalkyl malonates 3 with moderate stereoselectivity.The ester group of 3 was selectively reduced to afford optically active α-methyltropic acid (5) in good yield.The relationship between the structure of ammonium cations and the direction of stereoselectivity is described.