116393-76-1

Basic information

• Product Name: N-tert-butyloxycarbonyl-O-tosyl-L-homoserine benzyl ester
• Synonyms: N-tert-butyloxycarbonyl-O-tosyl-L-homoserine benzyl ester
• CAS NO: 116393-76-1
• Molecular Weight: 463.552
• Mol File: 116393-76-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-tert-butyloxycarbonyl-O-tosyl-L-homoserine benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-butyloxycarbonyl-O-tosyl-L-homoserine benzyl ester(116393-76-1)
• EPA Substance Registry System: N-tert-butyloxycarbonyl-O-tosyl-L-homoserine benzyl ester(116393-76-1)

Safety Data

• Hazardous Substances Data: 116393-76-1(Hazardous Substances Data)

Upstream product

• 92828-64-3 (R)-2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester 
• 41088-86-2 L-2-(tert-butyloxycarbonylamino)-4-hydroxybutyric acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 105183-60-6 (S)-benzyl 2-((tert-butoxycarbonyl)amino)-4-hydroxybutanoate 
• 98-59-9 p-toluenesulfonyl chloride 
• 68719-38-0 N-Boc-potassium L-homoserine 
• 133645-53-1 benzyl (2R)-(tert-butoxycarbonyl)amino-4-hydroxybutanoate 

Downstream Products

• 116393-81-8 O-benzenesulphonyl benzyl L-homoserine tosylate 
• 116393-79-4 O-tosyl L-homoserine benzyl ester tosylate 
• 853947-75-8 4-[tris(N-tert-butyloxycarbonyl)cyclen]-2-N-tert-butyloxycarbonylaminobutanoic acid benzyl ester 
• 95656-97-6 benzyl 4-bromo-2-<(tert-butyloxy)carbonylamino>butanoate 

Relevant articles and documents

2,4-diaminobutyric acid derivative and preparation method thereof

The invention relates to a 2,4-diaminobutyric acid derivative and a preparation method thereof and relates to the field of medicine synthesis. An aspartic acid derivative serves as an initiator, and the 2,4-diaminobutyric acid derivative is obtained through simple reduction and substitution reaction. Different from the prior art, a reagent adopted for the method is small in toxicity, reaction conditions are mild, requirements for a device are not high, synthesis steps are simple, the 2,4-diaminobutyric acid derivative can be obtained at a high total yield, and the 2,4-diaminobutyric acid derivative facilitates large-scale industrial production and can be well applied to medicine synthesis.

Synthesis and rearrangement of homoserine derivatives

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