116935-88-7Relevant articles and documents
Enzyme-mediated regioprotection-deprotection of hydroxyl groups in (+)-catechin
Lambusta,Nicolosi,Patti,Piattelli
, p. 1155 - 1158 (1993)
Several mono- and polyacetates of (+)-catechin [(2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-tri ol] have been synthesized by biocatalyzed reactions starting from (+)-catechin or (+)-catechin pentaacetate. In particular, 5-O-acetylcat
Regioselective hydrolysis of pentaacetyl catechin and epicatechin by porcine liver esterase
Basak, Amit,Mandal, Subrata,Bandyopadhyay, Saibal
, p. 1083 - 1085 (2003)
3,5,7,3′,4′-Pentaacetyl catechin was selectively hydrolyzed to either 3,7,3′,4′-tetraacetyl catechin or 3-acetyl catechin depending upon the duration of hydrolysis. A similar result was also obtained in the epicatechin series.
Studies on the porcine liver esterase-catalyzed hydrolysis of pentaacetyl catechin and epicatechin: Application to the synthesis of novel dimers and trimers
Basak, Amit,Das, Sanket,Bisai, Shrabani
experimental part, p. 4900 - 4903 (2009/05/27)
Porcine liver esterase-catalyzed hydrolysis of 3,5,7,3′,4′-pentaacetylated catechin was studied. The selectivity of the enzyme in hydrolyzing the acetate moiety is time dependent. Careful control of the duration of hydrolysis makes it possible to isolate the differentially protected catechins. Similar result was also obtained in the epicatechin series. These results are important for elaboration of epicatechin or catechin into different derivatives with defined regiochemistry. These include novel dimeric and trimeric architectures.