118492-87-8Relevant articles and documents
Baker's Yeast Reductions of β-Oxopyrrolidinecarboxylates: Synthesis of (+)-cis-(2R,3S)-3-Hydroxyproline and (-)-(1S,5S)-Geissman-Waiss Lactone, a Useful Precursor to Pyrrolizidine Alkaloids
Cooper, Jeremy,Gallagher, Peter T.,Knight, David W.
, p. 1313 - 1318 (1993)
Baker's yeast reduction of the β-oxo proline derivative 5 leads to the cis-hydroxy ester 6 and thence to (+)-cis-(2R,3S)-3-hydroxyproline 7, with >90percent enantiomeric enrichment.Subsequent one-carbon homologation leads to the (-)-Geissman-Waiss lactone
SUBSTITUTED N-(1H-INDAZOL-4-YL)IMIDAZO[1, 2-A]PYRIDINE-3- CARBOXAMIDE COMPOUNDS AS CFMS INHIBITORS
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Page/Page column 111, (2011/07/09)
Compounds of Formula (I): and pharmaceutically acceptable salts thereof in which R1, R2, R3, R4 and R5 have the meanings given in the specification, are inhibitors of cFMS and are useful in the treatment of bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases and pain.
Synthesis of rac-detoxinine
Hausler
, p. 982 - 992 (2007/10/02)
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