118517-06-9Relevant articles and documents
Peptide Bond Formation via Nα-Protected Diacyldiselenides
Vathsala,Roopesh Kumar,Sagar,Mahesh,Venkata Ramana,Sureshbabu, Vommina V.
, p. 653 - 658 (2018/04/26)
Abstract: A simple, straightforward, for the peptide bond formation employing corresponding carboxylic acids and amines derived from amino acids via Nα-protected diacyldiselenide is delineated. The key step of the synthesis is the in situ gener
Highly efficient amine organocatalysts based on bispidine for the asymmetric Michael addition of ketones to nitroolefins
Yang, Zhigang,Liu, Jie,Liu, Xiaohua,Wang, Zhen,Feng, Xiaoming,Su, Zhishan,Hua, Changwei
supporting information; experimental part, p. 2001 - 2006 (2009/08/14)
A highly diastereoselective and enantioselective Michael addition of cyclohexanone, acetone and other ketones to nitroolefins was developed by the use of an amine organocatalyst based on bispidine. Additionally, a theoretical study of transition structures revealed that this bispidinebased primary-secondary amine catalyst could serve through an enamine intermediate and H-bond interaction, which was important for the reactivity and selectivity of this reaction.
