118671-03-7

Basic information

• Product Name: (2-AMINO-4-METHOXYPHENYL)-ACETONITRILE
• Synonyms: (2-AMINO-4-METHOXYPHENYL)-ACETONITRILE
• CAS NO: 118671-03-7
• Molecular Formula: C₉H₁₀N₂O
• Molecular Weight: 162.19
• Mol File: 118671-03-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-AMINO-4-METHOXYPHENYL)-ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-AMINO-4-METHOXYPHENYL)-ACETONITRILE(118671-03-7)
• EPA Substance Registry System: (2-AMINO-4-METHOXYPHENYL)-ACETONITRILE(118671-03-7)

Safety Data

• Hazardous Substances Data: 118671-03-7(Hazardous Substances Data)

Usage

General Description

(2-Amino-4-methoxyphenyl)-acetonitrile is a chemical compound with the molecular formula C9H10N2O. It is a nitrile derivative of the amino acid tryptophan and is commonly used in the synthesis of pharmaceuticals and agrochemicals. (2-AMINO-4-METHOXYPHENYL)-ACETONITRILE has a wide range of applications in the pharmaceutical industry, particularly in the development of drugs for the treatment of various diseases and conditions. It can also be used as a building block in the production of other organic compounds. Additionally, (2-Amino-4-methoxyphenyl)-acetonitrile has potential applications in the field of organic electronics and materials science due to its unique properties.

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 10298-80-3 2-chloro-5-methoxynitrobenzene 
• 105003-90-5 (4-methoxy-2-nitro-phenyl)-acetonitrile 
• 65547-98-0 ethyl 2-cyano-2-(4-methoxy-2-nitrophenyl)acetate 
• 57559-52-1 4-methoxy-2-nitrobenzyl bromide 
• 17484-36-5 4-Methyl-3-nitroanisole 

Downstream Products

• 691900-59-1 6-methoxy-1H-indazole-3-carbonitrile 
• 691900-61-5 C₁₅H₁₂N₂O₂ 
• 118671-21-9 N-(2-Cyanomethyl-5-methoxy-phenyl)-acetamide 

Relevant articles and documents

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Synihesis of 3-substituied indoles via a modified madeling reaction

Anilides 4a-c,e-k, lla-d in which the amide function is benzylated, or silylated and having different electron-withdrawing groups (EWG) at the methyl methyl in the ortho position of the amide function, cyclize under the influence of potassium tert-butoxide to the corresponding indole derivatives 5a-c,e-k and 9a-d, respectively, under these conditions the chloroacetamides 4d,n and 11e are converted into the tetrahydroquinolines 6a,b and 12, respectively. Treatment of chloroacetamide 4m with KOt-Bu gave, in addition to starting material, indole 5m, tetrahydroquinoline 6c and 2(1H)-quinolinone 7. When 3-indolecarbonitrile 5a is treated with sodium in liquid amnonia debenzylation takes place, while after catalytic hydrogenation with 5% Pd/C the corresponding 2,3-dirnethylindole 8 is formed.