1187932-04-2

Basic information

• Product Name: (S)-3-AMINOMETHYL-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID BENZYL ESTER
• Synonyms: 3-(S)-AMINOMETHYL-2-CBZ-1,2,3,4-TETRAHYDRO-ISOQUINOLINE;(S)-3-AMINOMETHYL-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID BENZYL ESTER
• CAS NO: 1187932-04-2
• Molecular Formula: C₁₈H₂₀N₂O₂
• Molecular Weight: 296.36
• Mol File: 1187932-04-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-3-AMINOMETHYL-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID BENZYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-AMINOMETHYL-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID BENZYL ESTER(1187932-04-2)
• EPA Substance Registry System: (S)-3-AMINOMETHYL-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID BENZYL ESTER(1187932-04-2)

Safety Data

• Hazardous Substances Data: 1187932-04-2(Hazardous Substances Data)

Usage

General Description

(S)-3-aminomethyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester is a chemical compound with the molecular formula C20H22N2O3. It is a benzyl ester derivative of an isoquinoline carboxylic acid, which makes it a potential building block for the synthesis of various pharmaceutical compounds. (S)-3-AMINOMETHYL-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID BENZYL ESTER has the potential to exhibit biological activity due to its structural properties, and its use in medicinal chemistry research can lead to the development of new drugs for various therapeutic applications. Additionally, its pharmacological properties and potential applications in drug discovery make it an important chemical compound for further investigation in the field of pharmaceutical sciences.

Upstream product

• 501-53-1 benzyl chloroformate 
• 1238366-03-4 C₁₈H₁₈N₂O₃ 
• 79815-19-3 methyl (3S)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylate 

Downstream Products

• 54329-61-2 3-aminomethyl-1,2,3,4-tetrahydroisoquinoline dihydrochloride 
• 885273-85-8 [(3S)-1,2,3,4-tetrahydroisoquinoline-3-yl-methyl]carbamic acid tert-butyl ester 

Relevant articles and documents

Novel derivatives of indole and pyrrole, method for the production thereof and pharmaceutical compositions containing same

The invention relates to compounds of formula (I), wherein Ra, Rb, Rc, Rd, R3, R4, R5, A1, A2, T and W are as defined in the description. The invention also relates to drugs containing same.

PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I): wherein A1, A2, Ra, Rb, Rc, Rd, R3, R4, R5 and T are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.

Synthesis of (S)-3-aminoethyl-1,2,3,4-tetrahydroisoquinoline (TIQ-diamine) via the Mitsunobu protocol

The synthesis of (S)-3-Aminoethyl-1, 2, 3, 4-tetrahydroisoquinoline (TIQ-diamine) was successfully achieved via the Mitsunobu protocol. The method from earlier reports utilizing aminolysis of commercially available TIQ-amino methyl ester, and reduction of