1190-79-0Relevant articles and documents
An alternative pathway for production of acetonitrile: Ruthenium catalysed aerobic dehydrogenation of ethylamine
Corker, Emily C.,Mentzel, Uffe V.,Mielby, Jerrik,Riisager, Anders,Fehrmann, Rasmus
, p. 928 - 933 (2013)
The oxidative synthesis of acetonitrile from ethylamine was studied using a supported ruthenium catalyst. The reaction was conducted in both batch and flow processes and high conversions (over 85%) were achieved in both cases. Selectivity of both reactions was improved by optimisation of reaction conditions, achieving over 90% selectivity in the batch process and 80% selectivity in the continuous flow process. The use of a selective solid catalyst that utilises a feedstock that can be derived from biomass, dioxygen as the oxidant and water as the solvent represents a new, green route for the independent and efficient production of acetonitrile.
Mechanistic insights into the oxidative dehydrogenation of amines to nitriles in continuous flow
Corker, Emily C.,Ruiz-Martínez, Javier,Riisager, Anders,Fehrmann, Rasmus
, p. 5008 - 5015 (2015/11/03)
The oxidative dehydrogenation of various aliphatic amines to their corresponding nitrile compounds using RuO2/Al2O3 catalysts in air was successfully applied to a continuous flow reaction. Conversions of amines (up to >99%) and yields of nitriles (up to 77%) varied depending on reaction conditions and the amine utilised. The presence of water was found to be important for the activity and stability of the RuO2/Al2O3 catalyst. The Hammett relationship and in situ infrared spectroscopy were applied to divulge details about the catalytic mechanism of the oxidative dehydrogenation of amines over RuO2/Al2O3 catalysts.
A mild, aromatization of cyclic compounds and oxidation of amino groups to carbonyls using o-iodoxybenzoic acid
Kacan,Cicek,Karabulut,Ozyildirim
, p. 7649 - 7650 (2013/08/23)
A new, mild and efficient method has been developed for the synthesis of aromatic compounds and some carbonyls via the oxidative aromatization of amino cyclic compound by using hypervalent iodine reagent in DMSO at ambient temperature. The facile synthetic accessibility and it is as mild as non-hazardous nature render o-iodoxybenzoic acid equivalent of Dess-Martin periodinane reagent in organic oxidations.