1190363-45-1 Usage
General Description
"(R)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-one" is a chemical compound with a molecular formula C21H39NO2Si. It is a derivative of a cyclohepta[b]pyridin-5-one with a triisopropylsilyl group attached to the oxygen atom. (R)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-one is a white solid and is mainly used as a reagent in organic synthesis. It has been utilized in the development of new pharmaceuticals and agrochemicals due to its unique structure and reactivity. Additionally, it has potential applications in medicinal chemistry and the creation of novel materials.
Check Digit Verification of cas no
The CAS Registry Mumber 1190363-45-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,0,3,6 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1190363-45:
(9*1)+(8*1)+(7*9)+(6*0)+(5*3)+(4*6)+(3*3)+(2*4)+(1*5)=141
141 % 10 = 1
So 1190363-45-1 is a valid CAS Registry Number.
1190363-45-1Relevant articles and documents
Efficient and scalable enantioselective synthesis of a CGRP antagonist
Leahy, David K.,Fan, Yu,Desai, Lopa V.,Chan, Collin,Zhu, Jason,Hanson, Ronald L.,Sugiyama, Masano,Rosner, Thorsten,Cuniere, Nicolas,Guo, Zhiwei,Hsiao, Yi,Luo, Guanglin,Chen, Ling,Gao, Qi
supporting information, p. 4938 - 4941,4 (2012/12/12)
An enantioselective synthesis of the CGRP antagonist BMS-846372, amenable to large scale preparation, is presented. This new synthesis showcases a chemo- and enantioselective reduction of a cyclohepta[b]pyridine-5,9-dione as well as a Pd-catalyzed alpha-arylation reaction to form the key carbon-carbon bond and set the absolute and relative stereochemistry.
