119584-76-8 Usage
General Description
2,4-Diamino-5-iodoquinazoline is a chemical compound that belongs to the quinazoline class. It is characterized by the presence of two amino groups and an iodine atom attached to a quinazoline ring. 2 4-DIAMINO-5-IODOQUINAZOLINE has potential application in the field of medicinal chemistry due to its structural features. It can be used as a building block for the synthesis of various pharmaceutical compounds and could potentially exhibit biological activity. Researchers may be interested in studying its properties and exploring its potential as a drug candidate. Overall, 2,4-Diamino-5-iodoquinazoline is a valuable chemical with potential applications in medicinal chemistry and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 119584-76-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,5,8 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 119584-76:
(8*1)+(7*1)+(6*9)+(5*5)+(4*8)+(3*4)+(2*7)+(1*6)=158
158 % 10 = 8
So 119584-76-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H7IN4/c9-4-2-1-3-5-6(4)7(10)13-8(11)12-5/h1-3H,(H4,10,11,12,13)
119584-76-8Relevant articles and documents
2,4-DIAMINOQUINAZOLINES FOR SPINAL MUSCULAR ATROPHY
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Page/Page column 34, (2010/02/15)
2,4-Diaminoquinazolines of formulae I-IV and VI (I, II, III, IV and VI) are useful for treating spinal muscular atrophy (SMA).
Direct Synthesis of 2,4-Diaminoquinazolines from 2-Fluorobenzonitriles
Hynes, John B.,Pathak, Alpana,Panos, Constantina H.,Okeke, Claudia C.
, p. 1173 - 1177 (2007/10/02)
In a search for new methods for preparing 2,4-diaminoquinazolines having a diversity of substituents in the benzenoid ring, it was found that the reaction of 2,6-difluorbenzonitrile with guanidine carbonate gave 2,4-diamino-5-fluoroquinazoline in excellent yield.Extension of this approach to other 2-fluorobenzonitriles, some of which were elaborated for the first time, showed that this reaction possesses considerable generality.The cyclization was sucessful even when electron donating groups were present at position six.Only in two cases where a primary or secondary amino group was also present ortho to the cyano group was this transformation unsucessful.
