137553-45-8

Basic information

• Product Name: 2,4-DIAMINOQUINAZOLINE-5-CARBONITRILE
• Synonyms: 2,4-DIAMINOQUINAZOLINE-5-CARBONITRILE
• CAS NO: 137553-45-8
• Molecular Formula: C₉H₇N₅
• Molecular Weight: 185.19
• Mol File: 137553-45-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4-DIAMINOQUINAZOLINE-5-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIAMINOQUINAZOLINE-5-CARBONITRILE(137553-45-8)
• EPA Substance Registry System: 2,4-DIAMINOQUINAZOLINE-5-CARBONITRILE(137553-45-8)

Safety Data

• Hazardous Substances Data: 137553-45-8(Hazardous Substances Data)

Upstream product

• 65610-13-1 3-fluoro-1,2-benzenedicarbonitrile 
• 593-85-1 diguanidine carbonate 
• 77326-36-4 2-amino-6-fluorobenzonitrile 
• 143-33-9 sodium cyanide 
• 119584-76-8 2,4-diamino-5-iodoquinazoline 

Downstream Products

• 161201-03-2 dimethyl N-<4-<<(2,4-diaminoquinazolin-5-yl)methyl>amino>benzoyl>-L-glutamate 

Relevant articles and documents

2,4-Diamino-5-substituted-quinazolines as inhibitors of a human dihydrofolate reductase with a site-directed mutation at position 22 and of the dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii

2,4-Diaminoquinazoline antifolates with a lipophilic side chain at the 5- position, and in one case with a classical (p-aminobenzoyl)-L-glutamate side chain, were synthesized as potentially selective inhibitors of a site- directed mutant of human dihydrof