119871-52-2Relevant articles and documents
Oxidation of 1,2-Thiazoles: A Convenient Approach to 1,2-Thiazol-3(2H)-one 1,1-Dioxides
Schulze, Baerbel,Kirsten, Gisela,Kirrbach, Sabine,Rahm, Anette,Heimgartner, Heinz
, p. 1059 - 1070 (2007/10/02)
The 1,2-thiazoles obtained from 3-chloroalk-2-enals and ammonium thiocyanate (7-9, Scheme 1) are easily transformed to 1,2-thiazol-3(2H)-one 1,1-dioxides 10 on treatment with H2O2 in AcOH at 80 deg C.Hydrogenation of 10 in AcOH yields the corresponding sa