1210430-94-6

Basic information

• Product Name: 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate
• Synonyms: 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate
• CAS NO: 1210430-94-6
• Molecular Weight: 396.464
• Mol File: 1210430-94-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate(1210430-94-6)
• EPA Substance Registry System: 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate(1210430-94-6)

Safety Data

• Hazardous Substances Data: 1210430-94-6(Hazardous Substances Data)

Upstream product

• 611-71-2 (R)-Mandelic Acid 
• 112101-81-2 5-((R)-2-amino-1-propyl)-2-methoxybenzenesulphonamide 
• 112244-38-9 (+/-)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide 

Downstream Products

• 112101-81-2 5-((R)-2-amino-1-propyl)-2-methoxybenzenesulphonamide 
• 1391850-38-6 2-methoxy-5-[(2R)-2-(4-ethylpiperazin-1-yl)propyl]benzenesulfonamide 
• 1391850-34-2 2-methoxy-5-[(2R)-2-(4-methylpiperazin-1-yl)propyl]benzenesulfonamide 
• 1391850-36-4 2-methoxy-5-[(2R)-2-(piperazin-1-yl)propyl]benzenesulfonamide 

Relevant articles and documents

NOVEL PROCESS FOR THE SYNTHESIS OF ENANTIOMERICALLY PURE 2-METHOXY-5-[(2R)-2-(4-ALKYLPIPERAZIN-L-YL)PROPYL]-BENZENESULFONAMIDE

Where R is C1-C3 alkyl, alkenyl A novel process for synthesis of compound of Formula 1 comprising steroselective catalytic reduction of compound of Formula IV under hydrogen gas pressure to obtain an intermediate compound of Formula II, which on coupling in presence of coupling agent and base in presence of organic solvent to obtain compound of Formula X, Formula X on reacting with deprotecting agent in presence of organic solvent results in formation of compound of Formula XI, condensation of Formula XI with alkyl halide results in formation of compound of Formula I.