1212293-24-7 Usage
Uses
(S)-1-Benzylpyrrolidine-3-carboxylic Acid Hydrochloride is used as a reactant in the preparation of N-indolylalkyl heteroarylcarboxamide derivatives as TAU-induced toxicity inhibitors useful in the treatment of neurodegenerative diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 1212293-24-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,2,2,9 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1212293-24:
(9*1)+(8*2)+(7*1)+(6*2)+(5*2)+(4*9)+(3*3)+(2*2)+(1*4)=107
107 % 10 = 7
So 1212293-24-7 is a valid CAS Registry Number.
1212293-24-7Relevant articles and documents
A practical ex-chiral-pool synthesis of β-proline and homo-β-proline
Thomas, Christoph,Orecher, Florian,Gmeiner, Peter
, p. 1491 - 1496 (1998)
Starting from aspartic acid an efficient synthesis of enantiomerically pure β-proline and homo-β-proline is described. The key step of the synthesis includes formation of the 1,4-biselectrophile 6, followed by rearrangement via the aziridinium intermediate 7 and ring closure to give the pyrrolidinium salt 9a which can serve as a common precursor for both target compounds.
