159497-65-1

Basic information

• Product Name: L-Aspartic acid, N,N-bis(phenylmethyl)-, bis(phenylmethyl) ester
• CAS NO: 159497-65-1
• Molecular Formula: C32H31NO4
• Molecular Weight: 493.602
• Mol File: 159497-65-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Aspartic acid, N,N-bis(phenylmethyl)-, bis(phenylmethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Aspartic acid, N,N-bis(phenylmethyl)-, bis(phenylmethyl) ester(159497-65-1)
• EPA Substance Registry System: L-Aspartic acid, N,N-bis(phenylmethyl)-, bis(phenylmethyl) ester(159497-65-1)

Safety Data

• Hazardous Substances Data: 159497-65-1(Hazardous Substances Data)

Upstream product

• 70-47-3 L-asparagine 
• 100-39-0 benzyl bromide 

Downstream Products

• 229322-68-3 (2S,3S)-2-Dibenzylamino-3-methyl-butane-1,4-diol 
• 229322-69-4 (2S,3R)-2-Dibenzylamino-3-methyl-butane-1,4-diol 
• 229322-73-0 (2S,3R)-2-Allyl-3-dibenzylamino-butane-1,4-diol 
• 229322-72-9 (2S,3S)-2-Allyl-3-dibenzylamino-butane-1,4-diol 
• 229322-71-8 (2S,3R)-2-Dibenzylamino-3-propyl-butane-1,4-diol 
• 152298-99-2 (S)-1-(3-N,N-dibenzylamino-5-tert-butyldimethylsilyloxy)butyl-N-phthalimide 
• 152298-86-7 (S)-1-(3-N,N-dibenzylamino-4-tert-butyldimethylsilyloxy)butylmethanesulfonate 
• 152299-07-5 (S)-1-(3-N,N-dibenzylamino-4-hydroxy)butyl-N-phthalimide 
• 152299-00-8 (S)-N,N-dibenzyl-2-<1-tert-butyldimethylsilyloxy-4-(1-pyrazolyl)>butylamine 
• 152298-98-1 (S)-N,N-dibenzyl-2-(1-tert-butyldimethylsilyloxy-4-phenyl)butylamine 
• 161531-12-0 (S)-1-(3-N,N-dibenzylamino-4-hydroxy)butylmethanesulfonate 
• 152299-08-6 (S)-2-N,N-dibenzylamino-4-(1-pyrazolyl)-1-butanol 
• 152298-89-0 (S)-2-N,N-dibenzylamino-4-(1-pyrazolyl)butanal 
• 152298-87-8 (S)-N,N-dibenzyl-2-(1-tert-butyldimethylsilyloxy)pentylamine 

Relevant articles and documents

Chemo- and regioselective syntheses of enantiopure aminopyrrolidinones as building blocks for constrained peptidomimetics

Starting from natural asparagine the synthesis of the N-protected enantiomerically pure 3- and 4-aminopyrrolidinones (1) and (3) was accomplished. The incorporation of these building blocks into conformationally constrained peptidomimetics was demonstrated by the synthesis of the potential dopamine receptor modulator (14b) (β-PAOPA). Furthermore, Freidinger γ-lactams including the protected dipeptide mimetics (8a-c) and (9) were prepared. The optical integrity of the synthesis was established by NMR analysis of the ureas (10a,b).