122078-04-0Relevant articles and documents
SYNTHESIS OF N-ACETOXY-2-AMINONAPHTALINE, AN ULTIMATE CARCINOGEN OF THE CARCINOGENIC 2-NAPHTYLAMINE, AND ITS IN VITRO REACTIONS WITH (BIO)NUCLEOPHILES
Famulok, Michael,Bosold, Ferdinand,Boche, Gernot
, p. 321 - 324 (2007/10/02)
In this communication we describe (1) the synthesis of N-acetoxy-2-aminonaphtaline 4a (an ultimate carcinogen of the carcinogenic 2-naphtylamine), of N-pivaloyloxy-2-aminonaphtaline 4b, and (2) the reactions of 4a(b) with the nucleophiles N-methylaniline 6 and deoxyguanosine 7.Of special interest is the formation of the deoxyguanosine "adducts" 12-14.