1223405-86-4

Basic information

• Product Name: (2-nitrophenyl)acetic anhydride
• Synonyms: (2-nitrophenyl)acetic anhydride
• CAS NO: 1223405-86-4
• Molecular Weight: 344.28
• Mol File: 1223405-86-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-nitrophenyl)acetic anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: (2-nitrophenyl)acetic anhydride(1223405-86-4)
• EPA Substance Registry System: (2-nitrophenyl)acetic anhydride(1223405-86-4)

Safety Data

• Hazardous Substances Data: 1223405-86-4(Hazardous Substances Data)

Upstream product

• 3740-52-1 2-(2-nitrophenyl)acetic acid 

Downstream Products

• 1223405-87-5 1,2:5,6-di-O-isopropylidene-3-O-(2-nitro)phenylacetyl-α-D-glucofuranose 

Relevant articles and documents

(2-Nitrophenyl)acetyl: A new, selectively removable hydroxyl protecting group

Figure presented The utility of the (2-nitrophenyl)acetyl (NPAc) group for the protection of hydroxyl functions is reported. (2-Nitrophenyl)acetates are readily prepared starting from the commercially available, inexpensive (2-nitrophenyl)acetic acid, and these esters are stable under a series of common carbohydrate transformations. The NPAc group can be removed selectively using Zn and NH4Cl without affecting a series of common protecting groups. This new protecting group is orthogonal with the commonly used tert-butyldimethylsilyl, levulinoyl, 9-fluorenylmethoxycarbonyl, naphthylmethyl, and p-methoxybenzyl groups.