1224702-82-2Relevant articles and documents
NOVEL 4BETA-AMINO PODOPHYLLOTOXIN CONGENERS AS ANTI TUMOUR ANTIBIOTICS A PROCESS FOR THE PREPARATION THEREOF
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Page/Page column 7, (2011/09/20)
The present invention provides novel β-amino podophyllotoxin congeners of general formula (A); R═CH3, or H; R1=(a) or (b) or (c) or (d) or (e) or (f). The present invention also provides a process for the preparation of 4β-amino podo
Synthesis of 4β-N-polyaromatic substituted podophyllotoxins: DNA topoisomerase inhibition, anticancer and apoptosis-inducing activities
Kamal, Ahmed,Kumar, B. Ashwini,Suresh, Paidakula,Agrawal, Satyam Kumar,Chashoo, Gousia,Singh, Shashank K.,Saxena
experimental part, p. 8493 - 8500 (2011/02/24)
A new class of 4β-N-polyaromatic substituted podophyllotoxin congeners have been synthesized and evaluated for their DNA topoisomerase-II (topo-II) inhibition as well as anticancer potential in some human cancer cell lines. The ease of synthesis and inter