1227692-67-2Relevant articles and documents
Substituted pyrazolones require N2 hydrogen bond donating ability to protect against cytotoxicity from protein aggregation of mutant superoxide dismutase 1
Trippier, Paul C.,Benmohammed, Radhia,Kirsch, Donald R.,Silverman, Richard B.
supporting information, p. 6647 - 6650 (2013/01/14)
Amyotrophic lateral sclerosis (ALS) is a debilitating and fatal neurodegenerative disease. Although the cause remains unknown, misfolded protein aggregates are seen in neurons of sporadic ALS patients, and familial ALS mutations, including mutations in su
TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
-
Page/Page column 116, (2010/07/10)
The present invention relates to the identification of compounds and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the provided compounds.