123158-76-9

Basic information

• Product Name: 3-chloro-5-iodonitrobenzene
• Synonyms: 3-chloro-5-iodonitrobenzene;1-chloro-3-iodo-5-nitrobenzene;Benzene, 1-chloro-3-iodo-5-nitro-
• CAS NO: 123158-76-9
• Molecular Formula: C₆H₃ClINO₂
• Molecular Weight: 283.45099
• Mol File: 123158-76-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 70℃
• Boiling Point: 301 °C at 760 mmHg
• Flash Point: 135.8 °C
• Appearance: /
• Density: 2.094
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-chloro-5-iodonitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-5-iodonitrobenzene(123158-76-9)
• EPA Substance Registry System: 3-chloro-5-iodonitrobenzene(123158-76-9)

Safety Data

• Hazardous Substances Data: 123158-76-9(Hazardous Substances Data)

Usage

General Description

3-Chloro-5-iodonitrobenzene is a chemical compound that contains the elements chlorine, iodine, nitrogen, and carbon. It is a nitrobenzene derivative with a chlorine atom and an iodine atom attached to the benzene ring. 3-Chloro-5-iodonitrobenzene is used in organic synthesis as a starting material for the production of various pharmaceuticals, agrochemicals, and dyes. It is also used in the manufacturing of specialty chemicals and in research laboratories for its unique chemical properties. 3-Chloro-5-iodonitrobenzene is a highly reactive and potentially hazardous compound that requires careful handling and storage to prevent harm to human health and the environment.

Upstream product

• 89-63-4 4-Chloro-2-nitroaniline 
• 121-87-9 2-Chloro-4-nitroaniline 
• 7664-93-9 sulfuric acid 
• 146512-91-6 5-nitro-4-chloro-2-iodoaniline 
• 6280-88-2 4-chloro-2-nitro-benzoic acid 
• 88-74-4 2-nitro-aniline 
• 99-54-7 3,4-dichloronitrobenzene 
• 64-17-5 ethanol 
• 123158-75-8 2-amino-5-chloro-3-nitrophenyliodide 
• 110-46-3 isopentyl nitrite 
• 861609-74-7 2-chloro-6-iodo-4-nitroaniline 

Downstream Products

• 62606-14-8 1-chloro-3-(methylsulfonyl)-5-nitrobenzene 
• 62605-99-6 3-chloro-5-(methylsulfonyl)aniline 
• 83171-49-7 3-chloro-5-iodoaniline 

Relevant articles and documents

Pd-Catalyzed Decarboxylative Ortho-Halogenation of Aryl Carboxylic Acids with Sodium Halide NaX Using Carboxyl as a Traceless Directing Group

A highly regioselective Pd-catalyzed carboxyl directed decarboxylative ortho-C-H halogenation of cheap o-nitrobenzoic acids with NaX (X = I, Br) under aerobic conditions has been established. The utility of the method has been demonstrated by the gram-scale reaction and derivatization of the product. Experimental results have confirmed Pd and Bi played critical roles in the transformation and indicated the transformation might proceed via 2-halo-6-nitrobenzoic acid derivative intermediate.

Kynurenic acid derivatives useful in the treatment of neurodegenerative disorders

4-Oxo-1,4-dihydroquinoline compounds having a 2-acidic group or a group convertible thereto in vivo, and their pharmaceutically acceptable salts, are potent specific antagonists of N-methyl-D-aspartate (NMDA) receptors and are therefore useful in the treatment of neurodegenerative disorders. 4-Oxo-1,4-dihydroquinoline compounds having a 2-acidic group or a group convertible thereto in vivo, other than carboxy or C 1-6 alkoxycarbonyl, are novel compounds, as also are compounds of formula II STR1 wherein R 2 represents carboxy or a group convertible thereto in vivo, R 6 is hydrogen and R 5 and R 7 represent C 1-6 alkyl or halogen, provided that R 5 and R 7 are not simultaneously chlorine or simultaneously bromine; a process for preparing the novel compounds is described, as also are pharmaceutical compositions containing the novel compounds.